Human Vesicular glutamate transporter 1, SLC17A7 ELISA Kit | MyBioSource MBS932893 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Vesicular glutamate transporter 1, SLC17A7 ELISA Kit

catalog :

MBS932893

quantity :

48-Strip-Wells

price :

510 USD

product information

catalog number :

MBS932893

products type :

ELISA Kit

products full name :

Human Vesicular glutamate transporter 1, SLC17A7 ELISA Kit

products short name :

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter) , member 7

products name syn :

Human Vesicular glutamate transporter 1 (SLC17A7) ELISA kit; BNPI; VGLUT1; brain-specific Na-dependent inorganic phosphate cotransporter; solute carrier family 17; member 7; vesicular glutamate transporter 1; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter); member 7

other names :

vesicular glutamate transporter 1; Vesicular glutamate transporter 1; vesicular glutamate transporter 1; solute carrier family 17 member 7; brain-specific Na-dependent inorganic phosphate cotransporter; brain-specific Na(+)-dependent inorganic phosphate cotransporter; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; solute carrier family 17 (vesicular glutamate transporter), member 7; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 7

products gene name :

SLC17A7

other gene names :

SLC17A7; SLC17A7; BNPI; VGLUT1; BNPI; VGLUT1; VGluT1

uniprot entry name :

VGLU1_HUMAN

reactivity :

Human

sequence length :

560

specificity :

This assay has high sensitivity and excellent specificity for detection of Human SLC17A7. No significant cross-reactivity or interference between Human SLC17A7 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 18.75 pg/ml-1200 pg/ml. Sensitivity: 4.68 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Transport. Protein Biological Process 2: Anion transport. Protein Biological Process 3: Ion transport

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SLC17A7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SLC17A7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SLC17A7 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SLC17A7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

9945322

ncbi acc num :

NP_064705.1

ncbi gb acc num :

NM_020309.3

uniprot acc num :

Q9P2U7

ncbi mol weight :

61,613 Da

ncbi pathways :

Glutamate Neurotransmitter Release Cycle Pathway (106522); Glutamatergic Synapse Pathway (213818); Glutamatergic Synapse Pathway (213811); Neuronal System Pathway (106513); Neurotransmitter Release Cycle Pathway (106518); Nicotine Addiction Pathway (583255); Nicotine Addiction Pathway (584676); Organic Anion Transporters Pathway (119569); Retrograde Endocannabinoid Signaling Pathway (537443); Retrograde Endocannabinoid Signaling Pathway (539806)

ncbi summary :

The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]

uniprot summary :

SLC17A7: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Vesicle; Transporter. Chromosomal Location of Human Ortholog: 19q13. Cellular Component: synaptic vesicle membrane; presynaptic active zone; integral to membrane; plasma membrane; excitatory synapse; cell junction. Molecular Function: sodium:inorganic phosphate symporter activity; sodium-dependent phosphate transmembrane transporter activity; inorganic phosphate transmembrane transporter activity; L-glutamate transmembrane transporter activity. Biological Process: L-glutamate import; synaptic transmission, glutamatergic; synaptic transmission; glutamate secretion; long-term memory; phosphate transport; neurotransmitter secretion; ion transport; regulation of excitatory postsynaptic membrane potential; sequestering of neurotransmitter; transmembrane transport

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800