Human Tumor suppressor candidate 3, TUSC3 ELISA Kit | MyBioSource MBS9328777 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Tumor suppressor candidate 3, TUSC3 ELISA Kit

catalog :

MBS9328777

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9328777

products type :

ELISA Kit

products full name :

Human Tumor suppressor candidate 3, TUSC3 ELISA Kit

products short name :

[tumor suppressor candidate 3]

products name syn :

[Human Tumor suppressor candidate 3 (TUSC3) ELISA kit; D8S1992; M33; MGC13453; MRT7; N33; OST3A; OTTHUMP00000120036; Putative prostate cancer tumor suppressor; tumor suppressor candidate 3]

other names :

[tumor suppressor candidate 3 isoform a; Tumor suppressor candidate 3; tumor suppressor candidate 3; magnesium uptake/transporter TUSC3; oligosaccharyltransferase 3 homolog A; Putative prostate cancer tumor suppressor; tumor suppressor candidate 3; Magnesium uptake/transporter TUSC3; Protein N33]

products gene name :

[TUSC3]

other gene names :

[TUSC3; TUSC3; M33; N33; MRT7; MRT22; OST3A; D8S1992; N33]

uniprot entry name :

TUSC3_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of TUBB3 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

30410788

ncbi acc num :

NP_006756.2

ncbi gb acc num :

NM_006765.3

uniprot acc num :

Q13454

ncbi mol weight :

39,676 Da

ncbi pathways :

Asparagine N-linked Glycosylation Pathway (161013); Metabolism Of Proteins Pathway (106230); N-Glycan Biosynthesis Pathway (82975); N-Glycan Biosynthesis Pathway (345); Oligosaccharyltransferase Pathway (413373); Post-translational Protein Modification Pathway (161012); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)

ncbi summary :

This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

TUSC3: Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase. Defects in TUSC3 are the cause of mental retardation autosomal recessive type 7 (MRT7); also known as mental retardation non-syndromic autosomal recessive 7. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non- syndromic mental retardation patients do not manifest other clinical signs. Belongs to the OST3/OST6 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 8p22. Cellular Component: endoplasmic reticulum membrane; mitochondrion; integral to plasma membrane; oligosaccharyl transferase complex. Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity; magnesium ion transmembrane transporter activity. Biological Process: cellular protein metabolic process; cell redox homeostasis; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine; cognition; post-translational protein modification; magnesium ion transport. Disease: Mental Retardation, Autosomal Recessive 7

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095