Mouse Aryl hydrocarbon receptor nuclear transloCator-like protein 1, ARNTL ELISA Kit | MyBioSource MBS9328769 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Aryl hydrocarbon receptor nuclear transloCator-like protein 1, ARNTL ELISA Kit

catalog :

MBS9328769

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9328769

products type :

ELISA Kit

products full name :

Mouse Aryl hydrocarbon receptor nuclear transloCator-like protein 1, ARNTL ELISA Kit

products short name :

[aryl hydrocarbon receptor nuclear translocator-like]

products name syn :

[Mouse Aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) ELISA kit; BMAL1; BMAL1c; JAP3; MGC47515; MOP3; PASD3; TIC; bHLHe5; ARNT-like protein 1; brain and muscle; bHLH-PAS protein JAP3; basic-helix-loop-helix-PAS orphan MOP3; member of PAS superfamily 3; aryl hydrocarbon receptor nuclear translocator-like]

other names :

[aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform 2; Aryl hydrocarbon receptor nuclear translocator-like protein 1; aryl hydrocarbon receptor nuclear translocator-like protein 1; brain and muscle ARNT-like 1; aryl hydrocarbon receptor nuclear translocator-like; Arnt3; Brain and muscle ARNT-like 1]

products gene name :

[ARNTL]

other gene names :

[Arntl; Arntl; MOP3; Arnt3; Bmal1; BMAL1b; bHLHe5; bmal1b'; Bmal1]

uniprot entry name :

BMAL1_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of ARNTL (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

340007432

ncbi acc num :

NP_001229977.1

ncbi gb acc num :

NM_001243048.1

uniprot acc num :

Q9WTL8

ncbi mol weight :

69,452 Da

ncbi pathways :

Circadian Clock Pathway (575051); Circadian Exercise Pathway (198298); Circadian Repression Of Expression By REV-ERBA Pathway (575052); Circadian Rhythm - Mammal Pathway (83281); Circadian Rhythm - Mammal Pathway (495); Diurnally Regulated Genes With Circadian Orthologs Pathway (198406); Dopaminergic Synapse Pathway (469201); Dopaminergic Synapse Pathway (469185); Herpes Simplex Infection Pathway (377874); Herpes Simplex Infection Pathway (377865)

ncbi summary :

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]

uniprot summary :

BMAL1: aryl hydrocarbon receptor nuclear translocator-like protein. A circadian regulatory protein and substrate of casein kinase I epsilon. Heterodimers bind to an E-box element (3 -CACGTG-5 ), thereby activating transcription of PER1, and possibly of other circadian clock proteins. Seven splice isoforms have been reported. Protein type: Transcription factor; DNA-binding. Cellular Component: nuclear body; transcription factor complex; cytoplasm; nucleus. Molecular Function: protein dimerization activity; protein binding; signal transducer activity; DNA binding; aryl hydrocarbon receptor binding; protein heterodimerization activity; sequence-specific DNA binding; bHLH transcription factor binding; Hsp90 protein binding; transcription factor binding; transcription factor activity. Biological Process: circadian rhythm; transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of TOR signaling pathway; transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription, DNA-dependent; rhythmic process; response to redox state; positive regulation of circadian rhythm; signal transduction; negative regulation of fat cell differentiation; regulation of neurogenesis; regulation of transcription, DNA-dependent; protein import into nucleus, translocation; regulation of protein catabolic process; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; regulation of insulin secretion; regulation of hair cycle

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage