catalog number :
MBS9328486
products type :
ELISA Kit
products full name :
Human Keratin, type II cuticular Hb3, KRT83 ELISA Kit
products short name :
[keratin 83]
products name syn :
[Human Keratin; type II cuticular Hb3 (KRT83) ELISA kit; HB3; Hb-3; KRTHB3; MGC141663; hHb3; hard keratin; type II; 3; keratin; hair; basic; 3; keratin 83]
other names :
[keratin, type II cuticular Hb3; Keratin, type II cuticular Hb3; keratin, type II cuticular Hb3; K83; hHb3; keratin-83; hair keratin K2.10; type-II keratin Kb23; keratin, hair, basic, 3; hard keratin, type II, 3; type II hair keratin Hb3; keratin 83; Hair keratin K2.10; Keratin-83; K83; Type II hair keratin Hb3; Type-II keratin Kb23]
products gene name :
[KRT83]
other gene names :
[KRT83; KRT83; HB3; Hb-3; KRTHB3; KRTHB3; K83]
uniprot entry name :
KRT83_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KRT83 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002273.3
ncbi gb acc num :
NM_002282.3
ncbi mol weight :
54,195 Da
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008]
uniprot summary :
K83: Defects in KRT83 are a cause of monilethrix (MLTRX). Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected. Belongs to the intermediate filament family. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: extracellular space; keratin filament. Molecular Function: structural molecule activity. Biological Process: epidermis development; hair cycle; aging. Disease: Monilethrix
size4 :
10x96-Strip-Wells