catalog number :
MBS9328479
products type :
ELISA Kit
products full name :
Human Tyrosine-protein kinase Fer, FER ELISA Kit
products short name :
[fer (fps/fes related) tyrosine kinase]
products name syn :
[Human Tyrosine-protein kinase Fer (FER) ELISA kit; TYK3; phosphoprotein NCP94; fer (fps/fes related) tyrosine kinase]
other names :
[tyrosine-protein kinase Fer; Tyrosine-protein kinase Fer; tyrosine-protein kinase Fer; p94-Fer; tyrosine kinase 3; phosphoprotein NCP94; proto-oncogene c-Fer; feline encephalitis virus-related kinase FER; protein phosphatase 1, regulatory subunit 74; truncated fer (fps/fes related) tyrosine kinase; fujinami poultry sarcoma/Feline sarcoma-related protein Fer; fer (fps/fes related) tyrosine kinase; Feline encephalitis virus-related kinase FER; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; Proto-oncogene c-Fer; Tyrosine kinase 3; p94-Fer]
products gene name :
[FER]
other gene names :
[FER; FER; FerT; TYK3; Pe1Fe3; Pe1Fe6; PPP1R74; Pe1Fe10; Pe1Fe13; TYK3]
uniprot entry name :
FER_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Rat Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of FECH (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005237.2
ncbi gb acc num :
NM_005246.2
ncbi mol weight :
94,638 Da
ncbi pathways :
Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); N-cadherin Signaling Events Pathway (137919); PDGFR-beta Signaling Pathway (138071); Signal Transduction Pathway (477114); Signaling By SCF-KIT Pathway (477120); Signaling Events Mediated By PTP1B Pathway (138017); Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway (138068)
ncbi summary :
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. [provided by RefSeq, Jul 2008]
uniprot summary :
Fer: a non-receptor tyrosine kinase of the Fer family. Regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Increased expression associated with prostate cancer proliferation, and antisense blocks soft agar growth. Protein type: Kinase, protein; Oncoprotein; EC 2.7.10.2; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group; Fer family. Chromosomal Location of Human Ortholog: 5q21. Cellular Component: microtubule cytoskeleton; extrinsic to internal side of plasma membrane; lamellipodium; cytoplasm; nuclear chromatin; cell cortex; nucleus; cell junction; cytosol; actin cytoskeleton. Molecular Function: protein binding; cadherin binding; protein-tyrosine kinase activity; gamma-catenin binding; non-membrane spanning protein tyrosine kinase activity; actin binding; protein phosphatase 1 binding; protein kinase binding; lipid binding; ATP binding; Rab GTPase binding; epidermal growth factor receptor binding. Biological Process: regulation of mast cell degranulation; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; diapedesis; tyrosine phosphorylation of Stat3 protein; platelet-derived growth factor receptor signaling pathway; negative regulation of mast cell activation during immune response; response to lipopolysaccharide; chemotaxis; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; positive regulation of cell proliferation; cell adhesion; cell differentiation; regulation of protein amino acid phosphorylation; cytokine and chemokine mediated signaling pathway; microtubule cytoskeleton organization and biogenesis; regulation of epidermal growth factor receptor signaling pathway; regulation of cell proliferation; cell proliferation; positive regulation of actin filament polymerization; cellular response to insulin stimulus; actin cytoskeleton reorganization; innate immune response; mitotic cell cycle; positive regulation of cell migration
size4 :
10x96-Strip-Wells