ELISA/assay

Mouse Membrane-bound transcription factor site-1 protease, MBTPS1 ELISA Kit

MBS9328450

48-Strip-Wells

470 USD

ELISA Kit

Mouse Membrane-bound transcription factor site-1 protease, MBTPS1 ELISA Kit

[membrane-bound transcription factor peptidase, site 1]

[Mouse Membrane-bound transcription factor site-1 protease (MBTPS1) ELISA kit; KIAA0091; MGC138711; MGC138712; PCSK8; S1P; SKI-1; membrane-bound transcription factor protease; site 1; membrane-bound transcription factor site-1 protease; site-1 protease; subtilisin/kexin isozyme-1; membrane-bound transcription factor peptidase; site 1]

[membrane-bound transcription factor site-1 protease; Membrane-bound transcription factor site-1 protease; membrane-bound transcription factor site-1 protease; S1P endopeptidase; endopeptidase S1P; subtilisin/kexin isozyme 1; subtilisin/kexin isozyme-1; subtilisin/kexin isozyme SKI-1; sterol-regulated luminal protease; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor peptidase, site 1; Endopeptidase S1P; Sterol-regulated luminal protease; Subtilisin/kexin isozyme 1; SKI-1]

[MBTPS1]

[Mbtps1; Mbtps1; S1P; Ski1; SKI-1; AV003995; mKIAA0091; 0610038M03Rik; S1p; Ski1; SKI-1]

MBTP1_MOUSE

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MBTPS1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

268836232

NP_001161382.1

NM_001167910.1

Q9WTZ2

117,457 Da

Activation Of Chaperones By ATF6-alpha Pathway (574953); Diabetes Pathways (574950); Disease Pathway (574923); NGF Processing Pathway (575362); Protein Processing In Endoplasmic Reticulum Pathway (167331); Protein Processing In Endoplasmic Reticulum Pathway (167190); Signal Transduction Pathway (575318); Signalling By NGF Pathway (575361); Unfolded Protein Response Pathway (574952)

MBTPS1: Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His- Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Belongs to the peptidase S8 family. Protein type: Protease; EC 3.4.21.112; Membrane protein, integral; Endoplasmic reticulum. Cellular Component: Golgi apparatus; Golgi stack; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; endopeptidase activity. Biological Process: steroid metabolic process; cholesterol metabolic process; regulation of transcription factor import into nucleus; lysosome organization and biogenesis; lipid metabolic process; proteolysis

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095