Mouse Pituitary homeobox 2, PITX2 ELISA Kit | MyBioSource MBS9328365 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Pituitary homeobox 2, PITX2 ELISA Kit

catalog :

MBS9328365

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9328365

products type :

ELISA Kit

products full name :

Mouse Pituitary homeobox 2, PITX2 ELISA Kit

products short name :

[paired-like homeodomain 2]

products name syn :

[Mouse Pituitary homeobox 2 (PITX2) ELISA kit; ARP1; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; MGC111022; MGC20144; Otlx2; PTX2; RGS; RIEG; RIEG1; RS; OTTHUMP00000163736; all1-responsive gene 1; paired-like homeodomain transcription factor 2; pituitary; paired-like homeodomain 2]

other names :

[pituitary homeobox 2 isoform c; Pituitary homeobox 2; pituitary homeobox 2; solurshin; BRX1 homeoprotein; ALL1-responsive protein ARP1; orthodenticle-like homeobox 2; paired-like homeodomain transcription factor Munc 30; paired-like homeodomain transcription factor 2; ALL1-responsive protein ARP1; BRX1 homeoprotein; Homeobox protein PITX2; Orthodenticle-like homeobox 2; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Solurshin]

products gene name :

[PITX2]

other gene names :

[Pitx2; Pitx2; Brx1; Ptx2; Rieg; Brx1b; Otlx2; Munc30; 9430085M16Rik; Arp1; Brx1; Otlx2; Ptx2; Rgs]

uniprot entry name :

PITX2_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PITX2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

109948275

ncbi acc num :

NP_001035967.1

ncbi gb acc num :

NM_001042502.2

uniprot acc num :

P97474

ncbi mol weight :

35,321 Da

ncbi pathways :

TGF-beta Signaling Pathway (83261); TGF-beta Signaling Pathway (475)

uniprot summary :

PITX2: Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo. Defects in PITX2 are the cause of Axenfeld-Rieger syndrome type 1 (RIEG1); also known as Rieger syndrome type 1. RIEG1 is an autosomal dominant defect characterized by hypodontia (partial anodontia), anal stenosis, hypertelorism, mental deficiency, agenesis of the facial bones, with malformation of the anterior chamber of the eye. Defects in PITX2 are the cause of iridogoniodysgenesis type 2 (IRID2); also known as iridogoniodysgenesis syndrome 2 (IGDS2). It is an autosomal dominant inherited disease. Defects in PITX2 are a cause of Peters anomaly (PAN). It is a congenital defect of the anterior chamber of the eye. Defects in PITX2 are associated with ring dermoid of cornea (RDC). RDC is an autosomal dominantly inherited syndrome characterized by bilateral annular limbal dermoids with corneal and conjunctival extension. Belongs to the paired homeobox family. Bicoid subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Cell cycle regulation; DNA-binding; Transcription factor; Motility/polarity/chemotaxis. Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus. Molecular Function: identical protein binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; chromatin DNA binding; phosphoprotein binding; chromatin binding; transcription factor binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; atrial cardiac muscle morphogenesis; positive regulation of transcription, DNA-dependent; heart development; multicellular organismal development; ventricular cardiac muscle cell development; neuron migration; negative regulation of transcription from RNA polymerase II promoter; regulation of cell migration; embryonic hindlimb morphogenesis; cardiac muscle cell differentiation; odontogenesis; regulation of transcription, DNA-dependent; embryonic digestive tract morphogenesis; extraocular skeletal muscle development; vasculogenesis; hypothalamus cell migration; myoblast fusion; positive regulation of DNA binding; cardiac muscle development; spleen development; anatomical structure morphogenesis; skeletal muscle development; Wnt receptor signaling pathway; camera-type eye development; in utero embryonic development; embryonic camera-type eye development; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; organ morphogenesis; subthalamic nucleus development; pituitary gland development; positive regulation of transcription from RNA polymerase II promoter; determination of left/right symmetry; lung development

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095