catalog number :
MBS9327892
products type :
ELISA Kit
products full name :
Human Transcription factor E2F7, E2F7 ELISA Kit
products short name :
[E2F transcription factor 7]
products name syn :
[Human Transcription factor E2F7 (E2F7) ELISA kit; FLJ12981; ; E2F transcription factor 7]
other names :
[transcription factor E2F7; Transcription factor E2F7; transcription factor E2F7; E2F-7; E2F transcription factor 7]
products gene name :
[E2F7]
other gene names :
[E2F7; E2F7; E2F-7]
uniprot entry name :
E2F7_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of E2F7 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_976328.2
ncbi gb acc num :
NM_203394.2
ncbi mol weight :
99,888 Da
ncbi pathways :
E2F Transcription Factor Network Pathway (137934)
ncbi summary :
E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 [PubMed 14633988]).[supplied by OMIM, May 2008]
uniprot summary :
E2F7: Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5 -TTTC[CG]CGC-3 . Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; Cell cycle regulation; DNA-binding. Chromosomal Location of Human Ortholog: 12q21.2. Cellular Component: transcription factor complex; nucleus. Molecular Function: identical protein binding; protein binding; transcription corepressor activity; transcription factor activity. Biological Process: negative regulation of cell proliferation; DNA damage response, signal transduction by p53 class mediator; transcription, DNA-dependent; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis; negative regulation of cytokinesis; placenta development
size4 :
10x96-Strip-Wells