catalog number :
MBS9327471
products type :
ELISA Kit
products full name :
Mouse Dimethylaniline monooxygenase [N-oxide-forming] 3, FMO3 ELISA Kit
products short name :
[flavin containing monooxygenase 3]
products name syn :
[Mouse Dimethylaniline monooxygenase [N-oxide-forming] 3 (FMO3) ELISA kit; FMOII; MGC34400; TMAU; dJ127D3.1; dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline oxidase 3; hepatic flavin-containing monooxygenase-3; flavin containing monooxygenase 3]
other names :
[dimethylaniline monooxygenase; Dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline monooxygenase [N-oxide-forming] 3; FMO 3; dimethylaniline oxidase 3; trimethylamine monooxygenase; hepatic flavin-containing monooxygenase 3; flavin containing monooxygenase 3; Dimethylaniline oxidase 3; Hepatic flavin-containing monooxygenase 3; FMO 3; Trimethylamine monooxygenase (EC:1.14.13.148)]
products gene name :
[FMO3]
other gene names :
[Fmo3; Fmo3; AW111792; FMO 3]
uniprot entry name :
FMO3_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FMO3 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_032056.1
ncbi gb acc num :
NM_008030.1
ncbi mol weight :
60,516 Da
ncbi pathways :
Biological Oxidations Pathway (640062); Drug Metabolism - Cytochrome P450 Pathway (83229); Drug Metabolism - Cytochrome P450 Pathway (427); FMO Oxidizes Nucleophiles Pathway (640074); Metabolism Pathway (639859); Phase 1 - Functionalization Of Compounds Pathway (640063); Nicotine Degradation II Pathway (143046)
uniprot summary :
FMO3: Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds. Defects in FMO3 are the cause of trimethylaminuria (TMAU); also known as fish-odor syndrome. TMAU is an inborn error of metabolism associated with an offensive body odor and caused by deficiency of FMO-mediated N-oxidation of amino- trimethylamine (TMA) derived from foodstuffs. Such individuals excrete relatively large amounts of TMA in their urine, sweat, and breath, and exhibit a fishy body odor characteristic of the malodorous free amine. Belongs to the FMO family. Protein type: Oxidoreductase; EC 1.14.13.148; EC 1.14.13.8; Xenobiotic Metabolism - drug metabolism - cytochrome P450. Cellular Component: membrane; intracellular membrane-bound organelle; endoplasmic reticulum; integral to membrane. Molecular Function: amino acid binding; N-ethylmaleimide reductase activity; FAD binding; malolactic enzyme activity; oxidoreductase activity; NADP binding; monooxygenase activity; sulfur oxygenase reductase activity; flavin-containing monooxygenase activity; F420H2 dehydrogenase activity. Biological Process: drug metabolic process
size4 :
10x96-Strip-Wells