catalog number :
MBS9327272
products type :
ELISA Kit
products full name :
Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 6, ENPP6 ELISA Kit
products short name :
ectonucleotide pyrophosphatase/phosphodiesterase 6
products name syn :
Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (ENPP6) ELISA kit; MGC33971; NPP6; B830047L21Rik; ectonucleotide pyrophosphatase/phosphodiesterase 6
other names :
ectonucleotide pyrophosphatase/phosphodiesterase family member 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; ectonucleotide pyrophosphatase/phosphodiesterase family member 6; NPP-6; E-NPP 6; GPC-Cpde; B830047L21Rik; glycerophosphocholine cholinephosphodiesterase; choline-specific glycerophosphodiester phosphodiesterase; ectonucleotide pyrophosphatase/phosphodiesterase 6; Choline-specific glycerophosphodiester phosphodiesterase; Glycerophosphocholine cholinephosphodiesterase; GPC-Cpde
products gene name :
ENPP6
other gene names :
ENPP6; ENPP6; NPP6; UNQ1889/PRO4334; E-NPP 6; NPP-6; GPC-Cpde
uniprot entry name :
ENPP6_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ENPP6 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_699174.1
ncbi gb acc num :
NM_153343.3
ncbi mol weight :
50,241 Da
ncbi pathways :
Ether Lipid Metabolism Pathway (82990); Ether Lipid Metabolism Pathway (365)
uniprot summary :
ENPP6: Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p- nitrophenyl thymidine 5 -monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. Protein type: Phosphodiesterase; Membrane protein, integral; Lipid Metabolism - ether lipid; Membrane protein, GPI anchor; Motility/polarity/chemotaxis; EC 3.1.4.38. Chromosomal Location of Human Ortholog: 4q35.1. Cellular Component: plasma membrane; extracellular region. Molecular Function: glycerophosphocholine cholinephosphodiesterase activity; phosphoric diester hydrolase activity; glycerophosphodiester phosphodiesterase activity. Biological Process: choline metabolic process; lipid metabolic process; lipid catabolic process