catalog number :
MBS9327168
products type :
ELISA Kit
products full name :
Human Lanosterol synthase, LSS ELISA Kit
products short name :
[lanosterol synthase (2, 3-oxidosqualene-lanosterol cyclase)]
products name syn :
[Human Lanosterol synthase (LSS) ELISA kit; FLJ25486; FLJ35015; FLJ39450; FLJ46393; OSC; 2; 3-epoxysqualene-lanosterol cyclase; lanosterol synthase; lanosterol synthase (2; 3-oxidosqualene-lanosterol cyclase)]
other names :
[lanosterol synthase isoform 1; Lanosterol synthase; lanosterol synthase; hOSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; OSC; hOSC]
products gene name :
[LSS]
other gene names :
[LSS; LSS; OSC; OSC; OSC; hOSC]
uniprot entry name :
ERG7_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LSS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001001438.1
ncbi gb acc num :
NM_001001438.2
ncbi mol weight :
83,309 Da
ncbi pathways :
Cholesterol Biosynthesis Pathway (198809); Cholesterol Biosynthesis Pathway (106142); Cholesterol Biosynthesis, Squalene 2,3-epoxide = Cholesterol Pathway (413390); Cholesterol Biosynthesis, Squalene 2,3-epoxide = Cholesterol Pathway (468282); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Steroid Biosynthesis Pathway (82937); Steroid Biosynthesis Pathway (298); Cholesterol Biosynthesis I Pathway (142267); Cholesterol Biosynthesis I Pathway (138627)
ncbi summary :
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
uniprot summary :
LSS: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Belongs to the terpene cyclase/mutase family. Protein type: Lipid Metabolism - steroid biosynthesis; EC 5.4.99.7; Isomerase. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: endoplasmic reticulum membrane; membrane; lipid particle. Molecular Function: lanosterol synthase activity. Biological Process: steroid metabolic process; cholesterol biosynthetic process. Disease: Cataract 44
size4 :
10x96-Strip-Wells