catalog number :
MBS9327158
products type :
ELISA Kit
products full name :
Human Lysine-specific demethylase 6A, UTX ELISA Kit
products short name :
[ubiquitously transcribed tetratricopeptide repeat, X chromosome]
products name syn :
[Human Lysine-specific demethylase 6A (UTX) ELISA kit; RP13-886N14.3; DKFZp686A03225; MGC141941; UTX; bA386N14.2; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) ) ; ubiquitously-transcribed TPR gene on the X chromo; ubiquitously transcribed tetratricopeptide repeat; X chromosome]
other names :
[lysine-specific demethylase 6A isoform 3; Lysine-specific demethylase 6A; lysine-specific demethylase 6A; histone demethylase UTX; ubiquitously-transcribed TPR gene on the X chromosome; ubiquitously transcribed tetratricopeptide repeat protein X-linked; bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)); lysine (K)-specific demethylase 6A; Histone demethylase UTX; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein]
products gene name :
[UTX]
other gene names :
[KDM6A; KDM6A; UTX; KABUK2; bA386N14.2; UTX]
uniprot entry name :
KDM6A_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Camel Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 1.56nmol/L-50nmol/L. Sensitivity: 0.1nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of U-T4 (hereafter termed "analyte") in undiluted original Camel body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_066963.2
ncbi gb acc num :
NM_021140.3
ncbi mol weight :
154,177 Da
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
ncbi summary :
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
uniprot summary :
UTX: a nuclear protein that contains 8 tetratrico peptide repeat (TPRs). Processes involving TPR proteins include cell-cycle control, transcription repression, stress response, protein kinase inhibition, mitochondrial and peroxisomal protein transport and neurogenesis. Protein type: EC 1.14.11.-; Oxidoreductase. Chromosomal Location of Human Ortholog: Xp11.2. Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus. Molecular Function: identical protein binding; dioxygenase activity; metal ion binding. Biological Process: heart morphogenesis; notochord morphogenesis; respiratory system process; establishment and/or maintenance of chromatin architecture; regulation of gene expression; in utero embryonic development; multicellular organism growth; histone H3-K4 methylation; neural tube closure; mesodermal cell differentiation; Wnt receptor signaling pathway through beta-catenin; somite rostral/caudal axis specification. Disease: Kabuki Syndrome 2; Kabuki Syndrome 1
size4 :
10x96-Strip-Wells