product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Lysine-specific histone demethylase 1B (AOF1) ELISA Kit
catalog :
MBS9327045
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
product information
catalog number :
MBS9327045
products type :
ELISA Kit
products full name :
Human Lysine-specific histone demethylase 1B (AOF1) ELISA Kit
products short name :
[Lysine-specific histone demethylase 1B (AOF1)]
products name syn :
[amine oxidase (flavin containing) domain 1; RP1-298J15.1; AOF1; C6orf193; DKFZp686I0412; FLJ33898; FLJ34109; FLJ43328; LSD2; bA204B7.3; dJ298J15.2; amine oxidase (flavin containing) domain 1 amine oxidase; flavin containing 1]
other names :
[lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 1B; lysine-specific histone demethylase 1B; amine oxidase, flavin containing 1; lysine-specific histone demethylase 2; amine oxidase (flavin containing) domain 1; flavin-containing amine oxidase domain-containing protein 1; lysine (K)-specific demethylase 1B; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 2]
products gene name :
[AOF1]
other gene names :
[KDM1B; KDM1B; AOF1; LSD2; C6orf193; bA204B7.3; dJ298J15.2; AOF1; C6orf193; LSD2]
uniprot entry name :
KDM1B_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KDM1B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
116256451
ncbi acc num :
NP_694587.3
ncbi gb acc num :
NM_153042.3
uniprot acc num :
Q8NB78
ncbi mol weight :
92,098 Da
ncbi summary :
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
uniprot summary :
AOF1: Histone demethylase that demethylates Lys-4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated Lys-4 of histone H3. Has no effect on tri- methylated Lys-4 , mono-, di- or tri-methylated Lys-9 , mono-, di- or tri-methylated Lys-27 , mono-, di- or tri-methylated Lys- 36 of histone H3, or on mono-, di- or tri-methylated Lys-20 of histone H4. Belongs to the flavin monoamine oxidase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; EC 1.-.-.-. Chromosomal Location of Human Ortholog: 6p22.3. Cellular Component: nucleoplasm; nucleus. Molecular Function: DNA binding; FAD binding; zinc ion binding; oxidoreductase activity. Biological Process: establishment and/or maintenance of chromatin architecture; genetic imprinting; regulation of transcription, DNA-dependent; transcription, DNA-dependent; DNA methylation during gametogenesis; multicellular organismal development
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
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