catalog number :
MBS9326883
products type :
ELISA Kit
products full name :
Human Interferon-induced transmembrane protein 2, IFITM2 ELISA Kit
products short name :
interferon induced transmembrane protein 2 (1-8D)
products name syn :
Human Interferon-induced transmembrane protein 2 (IFITM2) ELISA kit; 1-8D; interferon-inducible; interferon induced transmembrane protein 2 (1-8D)
other names :
interferon-induced transmembrane protein 2; Interferon-induced transmembrane protein 2; interferon-induced transmembrane protein 2; dispanin subfamily A member 2c; interferon-inducible protein 1-8D; interferon induced transmembrane protein 2; Dispanin subfamily A member 2c; DSPA2c; Interferon-inducible protein 1-8D
products gene name :
IFITM2
other gene names :
IFITM2; IFITM2; 1-8D; DSPA2c; DSPA2c
uniprot entry name :
IFM2_HUMAN
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IFITM2 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples. Detection Range: The detection range of this kit is 31.2pg/ml-1000pg/ml.
other info2 :
Sensitivity: The sensitivity of this kit is 5.0pg/ml.
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IFITM2 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_006426.2
ncbi gb acc num :
NM_006435.2
ncbi mol weight :
14,632 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway 366171!!Immune System Pathway 106386!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104
uniprot summary :
Function: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.7 PublicationsManual assertion based on experiment in:Ref.5