catalog number :
MBS9326691
products type :
ELISA Kit
products full name :
Human Kremen protein 2, KREMEN2 ELISA Kit
products short name :
[kringle containing transmembrane protein 2]
products name syn :
[Human Kremen protein 2 (KREMEN2) ELISA kit; KRM2; MGC10791; MGC16709; kringle-containing transmembrane protein 2; kringle containing transmembrane protein 2]
other names :
[kremen protein 2 isoform e; Kremen protein 2; kremen protein 2; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; kringle containing transmembrane protein 2; Dickkopf receptor 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the nose]
products gene name :
[KREMEN2]
other gene names :
[KREMEN2; KREMEN2; KRM2; KRM2]
uniprot entry name :
KREM2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml-100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KRAS (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001240654.1
ncbi gb acc num :
NM_001253725.1
ncbi mol weight :
40,433 Da
ncbi pathways :
Presenilin Action In Notch And Wnt Signaling Pathway (137914); Wnt Signaling Network Pathway (137962)
ncbi summary :
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
KREMEN2: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: membrane; early endosome membrane; integral to membrane; plasma membrane. Biological Process: Wnt receptor signaling pathway; cell communication
size4 :
10x96-Strip-Wells