catalog number :
MBS9326668
products type :
ELISA Kit
products full name :
Human Tetraspanin-6, TSPAN6 ELISA Kit
products short name :
tetraspanin 6
products name syn :
Human Tetraspanin-6 (TSPAN6) ELISA kit; T245; TM4SF6; TSPAN-6; A15 homolog; tetraspan TM4SF; tetraspanin TM4-D; transmembrane 4 superfamily member 6; tetraspanin 6
other names :
tetraspanin-6 isoform d; Tetraspanin-6; tetraspanin-6; A15 homolog; tetraspan TM4SF; tetraspanin TM4-D; transmembrane 4 superfamily member 6; putative NF-kappa-B-activating protein 321; tetraspanin 6; A15 homolog; Putative NF-kappa-B-activating protein 321; T245 protein; Tetraspanin TM4-D; Transmembrane 4 superfamily member 6
products gene name :
TSPAN6
other gene names :
TSPAN6; TSPAN6; T245; TM4SF6; TSPAN-6; TM4SF6; UNQ767/PRO1560; Tspan-6
uniprot entry name :
TSN6_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TSPAN6 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001265672.1
ncbi gb acc num :
NM_001278743.1
ncbi mol weight :
27,563 Da
ncbi summary :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
uniprot summary :
TSPAN6: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: Xq22. Cellular Component: integral to membrane. Molecular Function: signal transducer activity; protein binding. Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction