catalog number :
MBS9326652
products type :
ELISA Kit
products full name :
Human BAG family molecular chaperone regulator 2, BAG2 ELISA Kit
products short name :
BCL2-associated athanogene 2
products name syn :
Human BAG family molecular chaperone regulator 2 (BAG2) ELISA kit; RP3-496N17.2; BAG-2; KIAA0576; MGC149462; dJ417I1.2; BAG-family molecular chaperone regulator-2; dJ417I1.2 (BAG-family molecular chaperone regulator 2) ; BCL2-associated athanogene 2
other names :
BAG family molecular chaperone regulator 2; BAG family molecular chaperone regulator 2; BAG family molecular chaperone regulator 2; bcl-2-associated athanogene 2; BAG-family molecular chaperone regulator-2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); BCL2-associated athanogene 2; Bcl-2-associated athanogene 2
products gene name :
BAG2
other gene names :
BAG2; BAG2; BAG-2; dJ417I1.2; BAG-2
uniprot entry name :
BAG2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BAG2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_004273.1
ncbi gb acc num :
NM_004282.3
ncbi mol weight :
23,772 Da
ncbi pathways :
Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)
ncbi summary :
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
uniprot summary :
BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Protein type: Apoptosis. Chromosomal Location of Human Ortholog: 6p12.1-p11.2. Molecular Function: identical protein binding; protein binding; chaperone binding. Biological Process: protein folding; protein metabolic process