catalog number :
MBS9326623
products type :
ELISA Kit
products full name :
Human Tyrosine-protein kinase transmembrane receptor ROR2, ROR2 ELISA Kit
products short name :
[receptor tyrosine kinase-like orphan receptor 2]
products name syn :
[Human Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2) ELISA kit; RP11-8I8.2; BDB; BDB1; MGC163394; NTRKR2; neurotrophic tyrosine kinase receptor-related 2; tyrosine-protein kinase transmembrane receptor ROR2; receptor tyrosine kinase-like orphan receptor 2]
other names :
[tyrosine-protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase transmembrane receptor ROR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2; receptor tyrosine kinase-like orphan receptor 2; Neurotrophic tyrosine kinase, receptor-related 2]
products gene name :
[ROR2]
other gene names :
[ROR2; ROR2; BDB; BDB1; NTRKR2; NTRKR2]
uniprot entry name :
ROR2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ROR2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_004551.2
ncbi gb acc num :
NM_004560.3
ncbi mol weight :
104,757 Da
ncbi pathways :
Noncanonical Wnt Signaling Pathway (169354); Wnt Signaling Pathway NetPath (198799); Wnt Signaling Network Pathway (137962)
ncbi summary :
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
uniprot summary :
ROR2: a receptor tyrosine kinase of the ROR family. May be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. Protein type: Protein kinase, tyrosine (receptor); Protein kinase, TK; Kinase, protein; Membrane protein, integral; EC 2.7.10.1; TK group; Ror family. Chromosomal Location of Human Ortholog: 9q22. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: Wnt-protein binding; protein binding; frizzled binding; transmembrane receptor protein tyrosine kinase activity; ATP binding. Biological Process: inner ear morphogenesis; somitogenesis; peptidyl-tyrosine phosphorylation; Wnt receptor signaling pathway, planar cell polarity pathway; multicellular organismal development; positive regulation of transcription, DNA-dependent; signal transduction; negative regulation of cell proliferation; Wnt receptor signaling pathway, calcium modulating pathway; JNK cascade; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; cartilage condensation; positive regulation of cell migration; embryonic genitalia morphogenesis. Disease: Robinow Syndrome, Autosomal Recessive; Brachydactyly, Type B1
size4 :
10x96-Strip-Wells