catalog number :
MBS9326561
products type :
ELISA Kit
products full name :
Human Differentially expressed in FDCP 6 homolog, DEF6 ELISA Kit
products short name :
[differentially expressed in FDCP 6 homolog (mouse)]
products name syn :
[Human Differentially expressed in FDCP 6 homolog (DEF6) ELISA kit; RP3-329A5.5; IBP; SLAT; SWAP70L; IRF4-binding protein; SWAP-70-like adaptor protein of T cells; differentially expressed in FDCP 6 homolog; differentially expressed in FDCP 6 homolog (mouse)]
other names :
[differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homolog; differentially expressed in FDCP 6 homolog; DEF-6; IRF4-binding protein; SWAP-70-like adaptor protein of T cells; differentially expressed in FDCP 6 homolog (mouse); IRF4-binding protein]
products gene name :
[DEF6]
other gene names :
[DEF6; DEF6; IBP; SLAT; SWAP70L; IBP; DEF-6]
uniprot entry name :
DEFI6_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Rat Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of DECR1 (hereafter termed "analyte") in undiluted original Rat body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_071330.3
ncbi gb acc num :
NM_022047.3
ncbi mol weight :
73,910 Da
ncbi pathways :
Regulation Of RAC1 Activity Pathway (169346); Regulation Of RhoA Activity Pathway (138070); T Cell Receptor Signaling Pathway (198862)
ncbi summary :
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]
uniprot summary :
DEF6: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling. Protein type: GEFs; GEFs, Rac/Rho. Chromosomal Location of Human Ortholog: 6p21.33-p21.1. Cellular Component: membrane; cytoplasm; plasma membrane; intercellular junction; nucleus
size4 :
10x96-Strip-Wells