catalog number :
MBS9326485
products type :
ELISA Kit
products full name :
Mouse E3 ubiquitin-protein ligase RNF128, RNF128 ELISA Kit
products short name :
[ring finger protein 128]
products name syn :
[Mouse E3 ubiquitin-protein ligase RNF128 (RNF128) ELISA kit; RP11-150F24.1; FLJ23516; GRAIL; gene related to anergy in lymphocytes; ring finger protein 128]
other names :
[E3 ubiquitin-protein ligase RNF128 isoform 2; E3 ubiquitin-protein ligase RNF128; E3 ubiquitin-protein ligase RNF128; gene related to anergy in lymphocytes protein; goliath-related E3 ubiquitin-protein ligase 1; ring finger protein 128; Gene related to anergy in lymphocytes protein; Goliath-related E3 ubiquitin-protein ligase 1; RING finger protein 128]
products gene name :
[RNF128]
other gene names :
[Rnf128; Rnf128; GRAIL; Greul1; AI987883; 1300002C13Rik; Grail; Greul1; MNCb-3816]
uniprot entry name :
RN128_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RNF128 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001241690.1
ncbi gb acc num :
NM_001254761.1
ncbi mol weight :
46,276 Da
uniprot summary :
RNF128: E3 ubiquitin-protein ligase that catalyzes polyubiquitin chains. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription and this activity is likely to be mediated by E3 ligase activity. Plays an important role in the induction of the anergic phenotype. Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural- inducing signals. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 6.3.2.-; EC 6.3.2.19; Membrane protein, integral; Ubiquitin ligase; Ligase; Ubiquitin conjugating system. Cellular Component: Golgi apparatus; cytoskeleton; membrane; endoplasmic reticulum; late endosome; cytoplasm; integral to membrane. Molecular Function: zinc ion binding; coenzyme F420-2 alpha-glutamyl ligase activity; metal ion binding; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; ribosomal S6-glutamic acid ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity. Biological Process: protein ubiquitination; negative regulation of cytokine biosynthetic process
size4 :
10x96-Strip-Wells