catalog number :
MBS9326376
products type :
ELISA Kit
products full name :
Human Macrophage receptor MARCO, MARCO ELISA Kit
products short name :
macrophage receptor with collagenous structure
products name syn :
Human Macrophage receptor MARCO (MARCO) ELISA kit; SCARA2; scavenger receptor class A; member 2; macrophage receptor with collagenous structure
other names :
macrophage receptor MARCO; Macrophage receptor MARCO; macrophage receptor MARCO; scavenger receptor class A member 2; scavenger receptor class A, member 2; macrophage receptor with collagenous structure; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2
products gene name :
MARCO
other gene names :
MARCO; MARCO; SCARA2; SCARA2
uniprot entry name :
MARCO_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MARCO (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_006761.1
ncbi gb acc num :
NM_006770.3
ncbi mol weight :
52,658 Da
ncbi pathways :
Phagosome Pathway (153910); Phagosome Pathway (153859)
ncbi summary :
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]
uniprot summary :
MARCO: Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q14.2. Cellular Component: collagen; integral to plasma membrane; plasma membrane. Molecular Function: transmembrane receptor activity; pattern recognition receptor activity; scavenger receptor activity. Biological Process: receptor-mediated endocytosis; cell surface receptor linked signal transduction; innate immune response; pattern recognition receptor signaling pathway; apoptotic cell clearance