catalog number :
MBS9326226
products type :
ELISA Kit
products full name :
Mouse Double C2-like domain-containing protein beta, DOC2B ELISA Kit
products short name :
[double C2-like domains, beta]
products name syn :
[Mouse Double C2-like domain-containing protein beta (DOC2B) ELISA kit; DOC2BL; double C2-like domains; beta-like; double C2-like domains; beta]
other names :
[double C2-like domain-containing protein beta; Double C2-like domain-containing protein beta; double C2-like domain-containing protein beta; doc2-beta; double C2 protein beta; double C2, beta]
products gene name :
[DOC2B]
other gene names :
[Doc2b; Doc2b; Doc2-beta]
uniprot entry name :
DOC2B_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DOC2B (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_031899.2
ncbi gb acc num :
NM_007873.2
ncbi mol weight :
45,853 Da
ncbi summary :
The protein encoded by this gene is a calcium sensor involved in glucose-stimulated insulin secretion, spontaneous neurotransmitter release, and enhanced SNARE-dependent vesicle fusion. [provided by RefSeq, Sep 2015]
uniprot summary :
DOC2B: Calcium sensor which positively regulates SNARE- dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes. Protein type: Lipid-binding. Cellular Component: SNARE complex; membrane; cell; cytoplasm; plasma membrane. Molecular Function: protein binding; clathrin binding; syntaxin binding; calcium-dependent phospholipid binding; calcium ion binding. Biological Process: vesicle fusion; positive regulation of calcium ion-dependent exocytosis; protein localization; synaptic vesicle exocytosis; calcium ion-dependent exocytosis of neurotransmitter; positive regulation of insulin secretion; positive regulation of vesicle fusion; regulation of calcium ion-dependent exocytosis
size4 :
10x96-Strip-Wells