catalog number :
MBS9326134
products type :
ELISA Kit
products full name :
Human Serine/arginine-rich splicing factor 5, SFRS5 ELISA Kit
products short name :
splicing factor, arginine/serine-rich 5
products name syn :
Human Serine/arginine-rich splicing factor 5 (SFRS5) ELISA kit; HRS; SRP40; ; splicing factor; arginine/serine-rich 5
other names :
serine/arginine-rich splicing factor 5; Serine/arginine-rich splicing factor 5; serine/arginine-rich splicing factor 5; SR splicing factor 5; delayed-early protein HRS; pre-mRNA-splicing factor SRP40; splicing factor, arginine/serine-rich 5; serine/arginine-rich splicing factor 5; Delayed-early protein HRS; Pre-mRNA-splicing factor SRP40; Splicing factor, arginine/serine-rich 5
products gene name :
SFRS5
other gene names :
SRSF5; SRSF5; HRS; SFRS5; SRP40; HRS; SFRS5; SRP40
uniprot entry name :
SRSF5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SFRS5 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001034554.1
ncbi gb acc num :
NM_001039465.1
ncbi mol weight :
31,264 Da
ncbi pathways :
Cleavage Of Growing Transcript In The Termination Region Pathway (106560); Gene Expression Pathway (105937); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); RNA Polymerase II Transcription Pathway (106557); RNA Polymerase II Transcription Termination Pathway (106559); Spliceosome Pathway (125136); Spliceosome Pathway (124832); Transport Of Mature Transcript To Cytoplasm Pathway (105959)
ncbi summary :
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2010]
uniprot summary :
SFRS5: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Belongs to the splicing factor SR family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Spliceosome; RNA-binding; RNA processing. Chromosomal Location of Human Ortholog: 14q24. Cellular Component: nucleoplasm; cytoplasm; nucleolus; nuclear speck; nucleus. Molecular Function: protein binding; RS domain binding; nucleotide binding. Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA splice site selection; mRNA export from nucleus; regulation of cell cycle; RNA splicing; response to wounding; gene expression; mRNA 3 -end processing; mRNA processing; termination of RNA polymerase II transcription