Mouse Transient receptor potential Cation channel subfamily V member 4, TRPV4 ELISA Kit | MyBioSource MBS9325844 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Transient receptor potential Cation channel subfamily V member 4, TRPV4 ELISA Kit

catalog :

MBS9325844

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9325844

products type :

ELISA Kit

products full name :

Mouse Transient receptor potential Cation channel subfamily V member 4, TRPV4 ELISA Kit

products short name :

[transient receptor potential cation channel, subfamily V, member 4]

products name syn :

[Mouse Transient receptor potential cation channel subfamily V member 4 (TRPV4) ELISA kit; OTRPC4; TRP12; VR-OAC; VRL-2; VRL2; VROAC; OSM9-like transient receptor potential channel 4; osmosensitive transient receptor potential channel 4; transient receptor potential channel 12; vanilloid rec; transient receptor potential cation channel; subfamily V; member 4]

other names :

[transient receptor potential cation channel subfamily V member 4; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel subfamily V member 4; trpv4 channel; osm-9-like TRP channel 4; vanilloid receptor-like channel 2; vanilloid receptor-like protein 2; transient receptor potential protein 12; osmosensitive transient receptor potential channel 4; vanilloid receptor-related osmotically-activated channel; transient receptor potential cation channel, subfamily V, member 4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; Vanilloid receptor-related osmotically-activated channel; VR-OAC]

products gene name :

[TRPV4]

other gene names :

[Trpv4; Trpv4; Trp12; VRL-2; VROAC; OTRPC4; VR-OAC; 0610033B08Rik; Trp12; Vrl2; Vroac; TrpV4; OTRPC4; TRP12; VR-OAC]

uniprot entry name :

TRPV4_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Horse Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of TRPV1 (hereafter termed "analyte") in undiluted original Horse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

269784723

ncbi acc num :

NP_071300.2

ncbi gb acc num :

NM_022017.3

uniprot acc num :

Q9EPK8

ncbi mol weight :

98,027 Da

uniprot summary :

TRPV4: a non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV4 sub-subfamily. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation. Cellular Component: cortical actin cytoskeleton; focal adhesion; cell surface; cell; integral to membrane; cytosol; cilium; growth cone; adherens junction; membrane; cytoplasmic microtubule; lamellipodium; plasma membrane; cytoplasmic vesicle; cell junction; filopodium. Molecular Function: microtubule binding; calcium channel activity; ion channel activity; nucleotide binding; beta-tubulin binding; actin binding; protein kinase binding; actin filament binding; calmodulin binding; protein binding; protein kinase C binding; osmosensor activity; cation channel activity; SH2 domain binding; alpha-tubulin binding; ATP binding. Biological Process: intercellular junction assembly; hypotonic response; actin filament organization; response to osmotic stress; regulation of response to osmotic stress; cellular calcium ion homeostasis; osmosensory signaling pathway; vasopressin secretion; positive regulation of microtubule depolymerization; elevation of cytosolic calcium ion concentration; hyperosmotic salinity response; transport; calcium ion transport; actin cytoskeleton reorganization; ion transport; cortical microtubule organization and biogenesis; transmembrane transport; microtubule polymerization

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage