Rat Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit | MyBioSource MBS9325630 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit

catalog :

MBS9325630

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9325630

products type :

ELISA Kit

products full name :

Rat Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit

products short name :

[acyl-Coenzyme A oxidase 1, palmitoyl]

products name syn :

[Rat Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) ELISA kit; ACOX; MGC1198; PALMCOX; SCOX; acyl-CoA oxidase; straight-chain; acyl-Coenzyme A oxidase 1; peroxisomal fatty acyl-CoA oxidase; acyl-Coenzyme A oxidase 1; palmitoyl]

other names :

[peroxisomal acyl-coenzyme A oxidase 1; Peroxisomal acyl-coenzyme A oxidase 1; peroxisomal acyl-coenzyme A oxidase 1; AOX; palmitoyl-CoA oxidase; acyl-Coenzyme A oxidase 1, palmitoyl; acyl-CoA oxidase 1, palmitoyl; Palmitoyl-CoA oxidaseCleaved into the following 3 chains:Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]

products gene name :

[ACOX1]

other gene names :

[Acox1; Acox1; RATACOA1; Acox; AOX]

uniprot entry name :

ACOX1_RAT

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Plant Tissue Homogenate And Biological Fluids Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of A-CoA (hereafter termed this analyte) in undiluted original Plant Tissue Homogenate and Biological Fluids samples.

ncbi gi num :

8394149

ncbi acc num :

NP_059036.1

ncbi gb acc num :

NM_017340.2

uniprot acc num :

P07872

ncbi mol weight :

74,679 Da

ncbi pathways :

Beta-oxidation Of Very Long Chain Fatty Acids Pathway (573982); Biosynthesis Of Unsaturated Fatty Acids Pathway (83426); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Fatty Acid Metabolism Pathway (83328); Fatty Acid Metabolism Pathway (296); Metabolism Pathway (573935); Metabolism Of Lipids And Lipoproteins Pathway (573950); PPAR Signaling Pathway (83434); PPAR Signaling Pathway (450); Peroxisomal Lipid Metabolism Pathway (573979)

ncbi summary :

catalyzes the oxidation of fatty acyl CoA to trans-2-enoyl-CoA and peroxide [RGD, Feb 2006]

uniprot summary :

ACOX1: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA. Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - fatty acid; EC 1.3.3.6; Oxidoreductase; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - alpha-linolenic acid. Cellular Component: nucleoplasm; peroxisomal membrane; mitochondrion; membrane; intracellular membrane-bound organelle; cytoplasm; nucleolus; plasma membrane; peroxisome; nucleus. Molecular Function: palmitoyl-CoA oxidase activity; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; FAD binding; protein N-terminus binding; fatty acid binding; receptor binding; PDZ domain binding. Biological Process: peroxisome fission; fatty acid beta-oxidation using acyl-CoA oxidase; generation of precursor metabolites and energy; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; lipid homeostasis; spermatogenesis; fatty acid oxidation; lipid metabolic process; prostaglandin metabolic process

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage