catalog number :
MBS9325462
products type :
ELISA Kit
products full name :
Human Histone H2A type 3, HIST3H2A ELISA Kit
products short name :
[histone cluster 3, H2a]
products name syn :
[Human Histone H2A type 3 (HIST3H2A) ELISA kit; MGC3165; histone 3; H2a; histone H2a; histone cluster 3; H2a]
other names :
[histone H2A type 3; Histone H2A type 3; histone H2A type 3; histone 3, H2a; histone cluster 3, H2a]
products gene name :
[HIST3H2A]
other gene names :
[HIST3H2A; HIST3H2A]
uniprot entry name :
H2A3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HIST3H2A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_254280.1
ncbi gb acc num :
NM_033445.2
ncbi mol weight :
14,121 Da
ncbi pathways :
Alcoholism Pathway (585563); Alcoholism Pathway (587116); Systemic Lupus Erythematosus Pathway (83122); Systemic Lupus Erythematosus Pathway (534)
ncbi summary :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Jul 2008]
uniprot summary :
HIST3H2A: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 1q42.13. Molecular Function: DNA binding; protein heterodimerization activity. Biological Process: nucleosome disassembly
size4 :
10x96-Strip-Wells