catalog number :
MBS9325454
products type :
ELISA Kit
products full name :
Mouse Neuronal membrane glycoprotein M6-a, GPM6A ELISA Kit
products short name :
glycoprotein M6A
products name syn :
Mouse Neuronal membrane glycoprotein M6-a (GPM6A) ELISA kit; GPM6; M6A; ; glycoprotein M6A
other names :
neuronal membrane glycoprotein M6-a isoform 2; Neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a; glycoprotein m6a
products gene name :
GPM6A
other gene names :
Gpm6a; Gpm6a; M6A; Gpm6; M6a; M6a
uniprot entry name :
GPM6A_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GPM6A (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001240683.1
ncbi gb acc num :
NM_001253754.1
ncbi mol weight :
31,149 Da
uniprot summary :
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family. Protein type: Membrane protein, integral; Cell surface; Membrane protein, multi-pass; Channel, calcium. Cellular Component: neuron projection; cell projection; cell soma; membrane; integral to membrane; plasma membrane; vesicle; filopodium. Molecular Function: calcium channel activity. Biological Process: positive regulation of filopodium formation; nervous system development; synaptogenesis; neuron migration; stem cell differentiation; neurite morphogenesis