catalog number :
MBS9325448
products type :
ELISA Kit
products full name :
Mouse Tropomyosin alpha-1 chain, TPM1 ELISA Kit
products short name :
[tropomyosin 1 (alpha)]
products name syn :
[Mouse Tropomyosin alpha-1 chain (TPM1) ELISA kit; C15orf13; CMD1Y; HTM-alpha; TMSA; alpha tropomyosin; cardiomyopathy; hypertrophic 3; sarcomeric tropomyosin kappa; tropomyosin 1 alpha chain; tropomyosin 1 (alpha)]
other names :
[tropomyosin alpha-1 chain isoform 1; Tropomyosin alpha-1 chain; tropomyosin alpha-1 chain; tropomyosin-1; alpha tropomyosin; alpha-tropomyosin; tropomyosin 1, alpha; Alpha-tropomyosin; Tropomyosin-1]
products gene name :
[TPM1]
other gene names :
[Tpm1; Tpm1; TM2; Tm3; Tmpa; Tpm-1; AA986836; AI854628; alpha-TM; Tpm-1; Tpma]
uniprot entry name :
TPM1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TPM1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001157720.1
ncbi gb acc num :
NM_001164248.1
ncbi mol weight :
32,681 Da
ncbi pathways :
Cardiac Muscle Contraction Pathway (93345); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121495); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114298); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Striated Muscle Contraction Pathway (198348)
uniprot summary :
TPM1: a cytoskeletal protein that binds to actin filaments in muscle and nonmuscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Defects in TPM3 are a cause of nemaline myopathy type 1 (NEM1). Three alternatively spliced isoforms have been described. Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor. Cellular Component: filamentous actin; protein complex; cytoskeleton; myofibril; cytoplasm; muscle thin filament tropomyosin. Molecular Function: actin filament binding; protein homodimerization activity; structural constituent of cytoskeleton; protein N-terminus binding; actin binding. Biological Process: positive regulation of cell adhesion; wound healing; actin filament capping; in utero embryonic development; muscle filament sliding; regulation of ATPase activity; embryonic development; positive regulation of ATPase activity; positive regulation of stress fiber formation; ruffle organization and biogenesis; ventricular cardiac muscle morphogenesis; negative regulation of cell migration; positive regulation of heart rate by epinephrine; cardiac muscle contraction
size4 :
10x96-Strip-Wells