product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Eukaryotic translation initiation factor 2-alpha kinase 4, EIF2AK4 ELISA Kit
catalog :
MBS9324956
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9324956
products type :
ELISA Kit
products full name :
Human Eukaryotic translation initiation factor 2-alpha kinase 4, EIF2AK4 ELISA Kit
products short name :
[eukaryotic translation initiation factor 2 alpha kinase 4]
products name syn :
[Human Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4) ELISA kit; GCN2; KIAA1338; GCN2 eIF2alpha kinase; eukaryotic translation initiation factor 2 alpha kinase 4]
other names :
[eukaryotic translation initiation factor 2-alpha kinase 4; Eukaryotic translation initiation factor 2-alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein; GCN2 eIF2alpha kinase; general control nonderepressible 2; eukaryotic translation initiation factor 2 alpha kinase 4; GCN2-like protein]
products gene name :
[EIF2AK4]
other gene names :
[EIF2AK4; EIF2AK4; GCN2; PVOD2; GCN2; KIAA1338]
uniprot entry name :
E2AK4_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EIF2AK4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
65287717
ncbi acc num :
NP_001013725.2
ncbi gb acc num :
NM_001013703.3
uniprot acc num :
Q9P2K8
ncbi mol weight :
186,911 Da
ncbi pathways :
Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Influenza A Pathway (217173); Influenza A Pathway (217150); Measles Pathway (213306); Measles Pathway (213277)
ncbi summary :
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
uniprot summary :
GCN2: a kinase of the PEK family. Phosphorylates and inhibits eukaryotic initiation factor (eIF)-2 alpha, providing an important protective mechanism during various cellular stress conditions including endoplasmic reticulum (ER) stress. Protein type: Protein kinase, Other; Translation; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Other group; PEK family; GCN2 subfamily. Chromosomal Location of Human Ortholog: 15q15.1. Molecular Function: protein serine/threonine kinase activity; ATP binding; eukaryotic translation initiation factor 2alpha kinase activity. Biological Process: unfolded protein response; negative regulation of translation; cellular response to starvation; protein amino acid phosphorylation; regulation of translational initiation. Disease: Pulmonary Venoocclusive Disease 2, Autosomal Recessive
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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