product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Protein sprouty homolog 4, SPRY4 ELISA Kit
catalog :
MBS9324592
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9324592
products type :
ELISA Kit
products full name :
Human Protein sprouty homolog 4, SPRY4 ELISA Kit
products short name :
sprouty homolog 4 (Drosophila)
products name syn :
Human Protein sprouty homolog 4 (SPRY4) ELISA kit; sprouty homolog 4; sprouty homolog 4 (Drosophila)
other names :
protein sprouty homolog 4 isoform 2; Protein sprouty homolog 4; protein sprouty homolog 4; sprouty homolog 4 (Drosophila)
products gene name :
SPRY4
other gene names :
SPRY4; SPRY4; HH17; Spry-4
uniprot entry name :
SPY4_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPRY4 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPRY4 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi gi num :
188595697
ncbi acc num :
NP_001120968.1
ncbi gb acc num :
NM_001127496.1
uniprot acc num :
Q9C004
ncbi mol weight :
32,541 Da
ncbi pathways :
Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)
ncbi summary :
This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
uniprot summary :
SPRY4: Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Belongs to the sprouty family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold; Inhibitor. Chromosomal Location of Human Ortholog: 5q31.3. Cellular Component: Golgi apparatus; focal adhesion; cytoplasm. Molecular Function: protein binding. Biological Process: negative regulation of MAP kinase activity; multicellular organismal development. Disease: Hypogonadotropic Hypogonadism 17 With Or Without Anosmia
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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