Human DCC-interacting protein 13-alpha, APPL1 ELISA Kit | MyBioSource MBS9324161 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human DCC-interacting protein 13-alpha, APPL1 ELISA Kit

catalog :

MBS9324161

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9324161

products type :

ELISA Kit

products full name :

Human DCC-interacting protein 13-alpha, APPL1 ELISA Kit

products short name :

[adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1]

products name syn :

[Human DCC-interacting protein 13-alpha (APPL1) ELISA kit; APPL; DIP13alpha; AKT2 interactor; adaptor protein containing pH domain; PTB domain and leucine zipper motif 1; signaling adaptor protein DIP13alpha; adaptor protein; phosphotyrosine interaction; PH domain and leucine zipper containing 1]

other names :

[DCC-interacting protein 13-alpha; DCC-interacting protein 13-alpha; DCC-interacting protein 13-alpha; dip13-alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1]

products gene name :

[APPL1]

other gene names :

[APPL1; APPL1; APPL; DIP13alpha; APPL; DIP13A; KIAA1428; Dip13-alpha]

uniprot entry name :

DP13A_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12ug/ml-100ug/ml. Sensitivity: 1.0ug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of APOM (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

6912242

ncbi acc num :

NP_036228.1

ncbi gb acc num :

NM_012096.2

uniprot acc num :

Q9UKG1

ncbi mol weight :

79,663 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198806); Apoptosis Pathway (105648); Colorectal Cancer Pathway (83106); Colorectal Cancer Pathway (518); Coregulation Of Androgen Receptor Activity Pathway (138085); EGFR1 Signaling Pathway (198782); Pathways In Cancer (83105); Regulation Of Apoptosis Pathway (105685); Role Of DCC In Regulating Apoptosis Pathway (161011)

ncbi summary :

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

uniprot summary :

APPL: an effector protein of the small GTPase Rab5, a key regulator of endocytosis. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Contains a PH domain and an N-terminal PID domain. Its interaction with RAB5A/Rab5 is essential for its recruitment to endosomal membranes as well as its role in cell proliferation. Binds DCC and the catalytic domain of the inactive form of AKT2 through its PID domain. Binds PIK3CA and subunits of the NuRD/MeCP1 complex. Phosphorylated upon DNA damage. Protein type: Nuclear receptor co-regulator; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 3p14.3. Cellular Component: early endosome membrane; cytoplasm; endosome membrane; NuRD complex; vesicle membrane; cytosol; nucleus. Molecular Function: protein kinase B binding; identical protein binding; protein binding. Biological Process: cell proliferation; positive regulation of apoptosis; insulin receptor signaling pathway; regulation of glucose import; signal transduction; cell cycle. Disease: Maturity-onset Diabetes Of The Young, Type 14

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage