catalog number :
MBS9324071
products type :
ELISA Kit
products full name :
Mouse DNA repair protein REV1, REV1 ELISA Kit
products short name :
[REV1 homolog (S. cerevisiae)]
products name syn :
[Mouse DNA repair protein REV1 (REV1) ELISA kit; FLJ21523; MGC163283; MGC26225; REV1L; REV1- like; REV1-like; REV1 homolog (S. cerevisiae)]
other names :
[DNA repair protein REV1; DNA repair protein REV1; DNA repair protein REV1; rev1-like terminal deoxycytidyl transferase; REV1 homolog (S. cerevisiae); Rev1-like terminal deoxycytidyl transferase]
products gene name :
[REV1]
other gene names :
[Rev1; Rev1; Rev1l; AU022044; 1110027I23Rik; Rev1l]
uniprot entry name :
REV1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of REV1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_062516.2
ncbi gb acc num :
NM_019570.3
ncbi mol weight :
137,341 Da
ncbi pathways :
DNA Damage Bypass Pathway (574973); DNA Repair Pathway (574958); Fanconi Anemia Pathway (377268); Fanconi Anemia Pathway (377128); Translesion Synthesis By DNA Polymerases Bypassing Lesion On DNA Template Pathway (574974); Translesion Synthesis By HREV1 Pathway (574975)
uniprot summary :
REV1L: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3 -end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Belongs to the DNA polymerase type-Y family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.7.7.-; Transferase; DNA repair, damage. Cellular Component: nucleus. Molecular Function: telomerase activity; CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase; DNA primase activity; metal ion binding; magnesium ion binding; DNA-directed DNA polymerase activity; mannose-phosphate guanylyltransferase activity; deoxycytidyl transferase activity; nucleotidyltransferase activity; transferase activity; tRNA guanylyltransferase activity; DNA binding; DNA/RNA helicase activity; RNA guanylyltransferase activity; sulfate adenylyltransferase activity; damaged DNA binding; RNA helicase activity; phospholactate guanylyltransferase activity. Biological Process: error-prone postreplication DNA repair; DNA repair; response to DNA damage stimulus; response to UV
size4 :
10x96-Strip-Wells