catalog number :
MBS9323979
products type :
ELISA Kit
products full name :
Human Muscleblind-like protein 3 (MBNL3) ELISA Kit
products short name :
[Muscleblind-like protein 3 (MBNL3)]
products name syn :
[muscleblind-like 3 (Drosophila); RP5-842K24.3; CHCR; FLJ11316; FLJ97142; MBLX; MBLX39; MBXL; Cys3His CCG1-required protein muscleblind-like 3]
other names :
[muscleblind-like protein 3 isoform 3; Muscleblind-like protein 3; muscleblind-like protein 3; muscleblind-like 3; Cys3His CCG1-required protein; muscleblind-like X-linked protein; muscleblind-like splicing regulator 3; Cys3His CCG1-required protein; Muscleblind-like X-linked protein; Protein HCHCR]
products gene name :
[MBNL3]
other gene names :
[MBNL3; MBNL3; CHCR; MBLX; MBXL; MBLX39; CHCR; MBLX39; MBXL]
uniprot entry name :
MBNL3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MBNL3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001164172.1
ncbi gb acc num :
NM_001170701.1
ncbi mol weight :
38,532 Da
ncbi summary :
This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009]
uniprot summary :
MBNL3: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction. Belongs to the muscleblind family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding. Chromosomal Location of Human Ortholog: Xq26.2. Cellular Component: cytoplasm; nucleus. Molecular Function: metal ion binding. Biological Process: regulation of RNA splicing; RNA splicing; multicellular organismal development; negative regulation of myoblast differentiation; mRNA processing
size4 :
10x96-Strip-Wells