catalog number :
MBS9323911
products type :
ELISA Kit
products full name :
Mouse Mitogen-activated protein kinase kinase kinase 12, MAP3K12 ELISA Kit
products short name :
mitogen-activated protein kinase kinase kinase 12
products name syn :
Mouse Mitogen-activated protein kinase kinase kinase 12 (MAP3K12) ELISA kit; DLK; MEKK12; MUK; ZPK; ZPKP1; dual leucine zipper kinase DLK; leucine zipper protein kinase; protein kinase MUK; zipper protein kinase; mitogen-activated protein kinase kinase kinase 12
other names :
mitogen-activated protein kinase kinase kinase 12; Mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; MAPK-upstream kinase; mixed lineage kinase; leucine-zipper protein kinase; zipper (leucine) protein kinase; dual leucine zipper bearing kinase; mitogen activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; Leucine-zipper protein kinase; ZPK; MAPK-upstream kinase; MUK; Mixed lineage kinase
products gene name :
MAP3K12
other gene names :
Map3k12; Map3k12; DLK; MUK; Zpk; Zpk; DLK; ZPK; MUK
uniprot entry name :
M3K12_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAPK12 (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001157115.1
ncbi gb acc num :
NM_001163643.1
ncbi mol weight :
96,084 Da
ncbi pathways :
Insulin Signaling Pathway (198368); MAPK Cascade Pathway (198366); MAPK Signaling Pathway (198294); MAPK Signaling Pathway (83245); MAPK Signaling Pathway (456)
uniprot summary :
DLK: May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Protein type: EC 2.7.11.25; Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; TKL group; MLK family; LZK subfamily. Cellular Component: growth cone; membrane; axon; cytoplasm; plasma membrane; cytosol. Molecular Function: transferase activity; protein serine/threonine kinase activity; protein homodimerization activity; MAP kinase kinase kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; ATP binding; protein kinase activity. Biological Process: peptidyl-serine phosphorylation; activation of MAPKK activity; protein amino acid autophosphorylation; histone phosphorylation; peptidyl-threonine phosphorylation; JNK cascade; phosphorylation; protein amino acid phosphorylation