This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human NACHT, LRR and PYD domains-containing protein 2, NLRP2 ELISA Kit
catalog :
MBS9323815
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9323815
products type :
ELISA Kit
products full name :
Human NACHT, LRR and PYD domains-containing protein 2, NLRP2 ELISA Kit
products short name :
[NLR family, pyrin domain containing 2]
products name syn :
[Human NACHT; LRR and PYD domains-containing protein 2 (NLRP2) ELISA kit; CLR19.9; FLJ20510; NALP2; NBS1; PAN1; PYPAF2; NACHT; LRR and PYD containing protein 2; NACHT; leucine rich repeat and PYD containing 2; PYRIN-Containing APAF1-like; nucleotide-binding oligomerization d; NLR family; pyrin domain containing 2]
other names :
[NACHT, LRR and PYD domains-containing protein 2 isoform 1; NACHT, LRR and PYD domains-containing protein 2; NACHT, LRR and PYD domains-containing protein 2; nucleotide-binding site protein 1; PYRIN-containing APAF1-like protein 2; NACHT, LRR and PYD containing protein 2; NACHT, leucine rich repeat and PYD containing 2; PYRIN domain and NACHT domain-containing protein 1; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2; NLR family, pyrin domain containing 2; Nucleotide-binding site protein 1; PYRIN domain and NACHT domain-containing protein 1; PYRIN-containing APAF1-like protein 2]
products gene name :
[NLRP2]
other gene names :
[NLRP2; NLRP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NALP2; NBS1; PAN1; PYPAF2]
uniprot entry name :
NALP2_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NLRP2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
291463275
ncbi acc num :
NP_001167552.1
ncbi gb acc num :
NM_001174081.1
uniprot acc num :
Q9NX02
ncbi mol weight :
120,515 Da
ncbi summary :
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
uniprot summary :
NLRP2: Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Belongs to the NLRP family. 4 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 19q13.42. Cellular Component: cytoplasm. Molecular Function: protein binding; ATP binding; Pyrin domain binding. Biological Process: positive regulation of caspase activity; positive regulation of interleukin-1 beta secretion
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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