Mouse UDP-glucuronosyltransferase 1-1, UGT1A1 ELISA Kit | MyBioSource MBS9323596 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse UDP-glucuronosyltransferase 1-1, UGT1A1 ELISA Kit

catalog :

MBS9323596

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9323596

products type :

ELISA Kit

products full name :

Mouse UDP-glucuronosyltransferase 1-1, UGT1A1 ELISA Kit

products short name :

[UDP glucuronosyltransferase 1 family, polypeptide A1]

products name syn :

[Mouse UDP-glucuronosyltransferase 1-1 (UGT1A1) ELISA kit; GNT1; HUG-BR1; UDPGT; UGT1; UGT1A; UDP glucuronosyltransferase 1A1; UDP glycosyltransferase 1 family; polypeptide A1; bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase is; UDP glucuronosyltransferase 1 family; polypeptide A1]

other names :

[UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-1; UDPGT; UGT1*1; UGT1-01; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1 family, member 1; UDP-glucuronosyltransferase 1 family, polypeptide A1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1A1; UGTBR1]

products gene name :

[UGT1A1]

other gene names :

[Ugt1a1; Ugt1a1; Gnt1; UgtBr1; UGT1A01; Udpgt-1a; UDPGT 1-1; Ugt1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1]

uniprot entry name :

UD11_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of UGT1A1 (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.

ncbi gi num :

145699099

ncbi acc num :

NP_964007.2

ncbi gb acc num :

NM_201645.2

uniprot acc num :

Q63886

ncbi mol weight :

60,047 Da

ncbi pathways :

Ascorbate And Aldarate Metabolism Pathway (83132); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate Biosynthesis, Animals, Glucose-1P = Ascorbate Pathway (421792); Ascorbate Biosynthesis, Animals, Glucose-1P = Ascorbate Pathway (468309); Biological Oxidations Pathway (574888); Drug Metabolism - Cytochrome P450 Pathway (83229); Drug Metabolism - Cytochrome P450 Pathway (427); Drug Metabolism - Other Enzymes Pathway (83230); Drug Metabolism - Other Enzymes Pathway (428); Estrogen Metabolism Pathway (198415)

uniprot summary :

UGT1A1: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4- methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Expressed in liver. Not expressed in skin or kidney. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing. Protein type: Transferase; Cofactor and Vitamin Metabolism - retinol; Membrane protein, integral; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - starch and sucrose; Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.4.1.17; Carbohydrate Metabolism - pentose and glucuronate interconversions. Cellular Component: endoplasmic reticulum membrane; membrane; intracellular membrane-bound organelle; integral to plasma membrane; endoplasmic reticulum; integral to membrane. Molecular Function: transferase activity; enzyme inhibitor activity; transferase activity, transferring glycosyl groups; enzyme binding; retinoic acid binding; protein homodimerization activity; transferase activity, transferring hexosyl groups; protein heterodimerization activity; glucuronosyltransferase activity; steroid binding. Biological Process: response to organic substance; flavonoid biosynthetic process; metabolic process; negative regulation of catalytic activity; flavone metabolic process; cellular response to hormone stimulus

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage