catalog number :
MBS9323584
products type :
ELISA Kit
products full name :
Human Transcription factor SOX-4, SOX4 ELISA Kit
products short name :
[SRY (sex determining region Y) -box 4]
products name syn :
[Human Transcription factor SOX-4 (SOX4) ELISA kit; EVI16; SRY-related HMG-box gene 4; ecotropic viral integration site 16; SRY (sex determining region Y) -box 4]
other names :
[transcription factor SOX-4; Transcription factor SOX-4; transcription factor SOX-4; SRY-related HMG-box gene 4; ecotropic viral integration site 16; SRY (sex determining region Y)-box 4]
products gene name :
[SOX4]
other gene names :
[SOX4; SOX4; EVI16]
uniprot entry name :
SOX4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Sheep Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SOX1 (hereafter termed "analyte") in undiluted original Sheep body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_003098.1
ncbi gb acc num :
NM_003107.2
ncbi mol weight :
47,263 Da
ncbi pathways :
IL-5 Signaling Pathway (198770)
ncbi summary :
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]
uniprot summary :
SOX4: Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5 -AACAAAG-3 motif. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 6p22.3. Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleus. Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; negative regulation of protein export from nucleus; positive regulation of translation; positive regulation of apoptosis; somatic stem cell maintenance; heart development; positive regulation of transcription, DNA-dependent; regulation of protein stability; Wnt receptor signaling pathway through beta-catenin; glucose homeostasis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; glial cell proliferation; negative regulation of cell proliferation; sympathetic nervous system development; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; skeletal development; positive regulation of Wnt receptor signaling pathway; T cell differentiation; glial cell development; pro-B cell differentiation; protein stabilization; positive regulation of insulin secretion; DNA damage response, detection of DNA damage; spinal cord motor neuron differentiation; endocrine pancreas development; limb bud formation; spinal cord development; negative regulation of protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter; neural tube formation
size4 :
10x96-Strip-Wells