catalog number :
MBS9323492
products type :
ELISA Kit
products full name :
Rat Lysine-specific demethylase 8, JMJD5 ELISA Kit
products short name :
[jumonji domain containing 5]
products name syn :
[Rat Lysine-specific demethylase 8 (JMJD5) ELISA kit; FLJ13798; ; jumonji domain containing 5]
other names :
[lysine-specific demethylase 8; Lysine-specific demethylase 8; lysine-specific demethylase 8; jumonji domain containing 5; jmjC domain-containing protein 5; jumonji domain-containing protein 5; lysine (K)-specific demethylase 8; JmjC domain-containing protein 5; Jumonji domain-containing protein 5]
products gene name :
[JMJD5]
other gene names :
[Kdm8; Kdm8; Jmjd5; RGD1304823; Jmjd5]
uniprot entry name :
KDM8_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of JMJD5 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001032273.1
ncbi gb acc num :
NM_001037196.1
ncbi mol weight :
47,247 Da
uniprot summary :
JMJD5: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated Lys-36 (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Demethylase; Cell cycle regulation; EC 1.14.11.27. Cellular Component: nucleus. Molecular Function: metal ion binding; histone demethylase activity (H3-K36 specific); chromatin binding. Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; G2/M transition of mitotic cell cycle
size4 :
10x96-Strip-Wells