Human Solute carrier organic anion transporter family member 1B1, SLCO1B1 ELISA Kit | MyBioSource MBS9323360 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Solute carrier organic anion transporter family member 1B1, SLCO1B1 ELISA Kit

catalog :

MBS9323360

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9323360

products type :

ELISA Kit

products full name :

Human Solute carrier organic anion transporter family member 1B1, SLCO1B1 ELISA Kit

products short name :

[solute carrier organic anion transporter family, member 1B1]

products name syn :

[Human Solute carrier organic anion transporter family member 1B1 (SLCO1B1) ELISA kit; LST-1; LST1; MGC133282; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6; liver-specific organic anion transporter 1; sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organ; solute carrier organic anion transporter family; member 1B1]

other names :

[solute carrier organic anion transporter family member 1B1; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family member 1B1; OATP-2; solute carrier family 21 member 6; liver-specific organic anion transporter 1; sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; solute carrier organic anion transporter family, member 1B1; Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solute carrier family 21 member 6]

products gene name :

[SLCO1B1]

other gene names :

[SLCO1B1; SLCO1B1; LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6; LST1; OATP1B1; OATP2; OATPC; SLC21A6; LST-1; OATP-2]

uniprot entry name :

SO1B1_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Rat Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SLC6A8 (hereafter termed "analyte") in undiluted original Rat body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

225543525

ncbi acc num :

NP_006437.3

ncbi gb acc num :

NM_006446.4

uniprot acc num :

Q9Y6L6

ncbi mol weight :

76,449 Da

ncbi pathways :

Bile Acid And Bile Salt Metabolism Pathway (106144); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Codeine And Morphine Metabolism Pathway (198831); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Recycling Of Bile Acids And Salts Pathway (106149); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Organic Anions Pathway (187186)

ncbi summary :

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

uniprot summary :

SLCO1B1: Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver. Defects in SLCO1B1 are a cause of hyperbilirubinemia, Rotor type (HBLRR). An autosomal recessive form of primary conjugated hyperbilirubinemia. Affected individuals develop mild jaundice not associated with hemolysis shortly after birth or in childhood. They have delayed plasma clearance of the unconjugated anionic dye bromsulphthalein and prominent urinary excretion of coproporphyrin I. Hepatic pigmentation is normal. Belongs to the organo anion transporter (TC 2.A.60) family. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter. Chromosomal Location of Human Ortholog: 12p. Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; plasma membrane. Molecular Function: sodium-independent organic anion transmembrane transporter activity. Biological Process: bile acid and bile salt transport; sodium-independent organic anion transport; bile acid metabolic process; transmembrane transport; organic anion transport. Disease: Hyperbilirubinemia, Rotor Type

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage