catalog number :
MBS9323287
products type :
ELISA Kit
products full name :
Mouse Dual specificity protein phosphatase 10, DUSP10 ELISA Kit
products short name :
[dual specificity phosphatase 10]
products name syn :
[Mouse Dual specificity protein phosphatase 10 (DUSP10) ELISA kit; MKP-5; MKP5; dual specificity phosphatase MKP-5; map kinase phosphatase 5; serine/threonine specific protein phosphatase; dual specificity phosphatase 10]
other names :
[dual specificity protein phosphatase 10; Dual specificity protein phosphatase 10; dual specificity protein phosphatase 10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; dual specificity phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5]
products gene name :
[DUSP10]
other gene names :
[Dusp10; Dusp10; MKP5; MKP-5; AI158871; 2610306G15Rik; Mkp5; MAP kinase phosphatase 5; MKP-5]
uniprot entry name :
DUS10_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DUSP10 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_071302.2
ncbi gb acc num :
NM_022019.5
ncbi mol weight :
52,532 Da
ncbi pathways :
MAPK Signaling Pathway (198294); MAPK Signaling Pathway (83245); MAPK Signaling Pathway (456)
uniprot summary :
MKP-5: a non-receptor, dual-specificity phosphoprotein phosphatase (DUSP). Different members of the DUSP family show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. Contains 1 rhodanese domain. Protein type: EC 3.1.3.16; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.48. Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleus. Molecular Function: MAP kinase phosphatase activity; hydrolase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity. Biological Process: negative regulation of oligodendrocyte differentiation; negative regulation of JNK activity; negative regulation of JNK cascade; regulation of adaptive immune response; dephosphorylation; oligodendrocyte differentiation; response to lipopolysaccharide; protein amino acid dephosphorylation; negative regulation of stress-activated MAPK cascade; inactivation of MAPK activity; regulation of innate immune response
size4 :
10x96-Strip-Wells