catalog number :
MBS9323257
products type :
ELISA Kit
products full name :
Mouse Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PPARGC1B ELISA Kit
products short name :
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
products name syn :
Mouse Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B) ELISA kit; ERRL1; PERC; PGC-1 (beta); PGC1B; PGC-1-related estrogen receptor alpha coactivator; peroxisome proliferative activated receptor; gamma; coactivator 1; beta; peroxisome proliferator-activated receptor gamma; coactivator 1 beta
other names :
peroxisome proliferator-activated receptor gamma coactivator 1-beta; Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1-beta; PGC-1beta; PGC-1-beta; ERR ligand 1; PPARGC-1-beta; PGC-1beta/ERRL1; PPAR-gamma coactivator 1-beta; PPAR gamma coactivator-1beta protein; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; ERR ligand 1
products gene name :
PPARGC1B
other gene names :
Ppargc1b; Ppargc1b; Perc; 4631412G21Rik; Errl1; Pgc1; Pgc1b; Ppargc1; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta
uniprot entry name :
PRGC2_MOUSE
ncbi acc num :
NP_573512.1
ncbi gb acc num :
NM_133249.2
ncbi mol weight :
112,075 Da
ncbi pathways :
Mitochondrial Gene Expression Pathway 198322!!SIDS Susceptibility Pathways 198328!!MRNA Processing Pathway 198369
uniprot summary :
Function: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty acids and ketogenesis during fasting. Stimulates SREBP-mediated lipogenic gene expression in the liver. Induces energy expenditure and antagonizes obesity when overexpressed. Induces also the expression of mitochondrial genes involved in oxidative metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.4 PublicationsManual assertion based on experiment in:Ref.1