ELISA/assay

Human Ran-binding protein 9, RANBP9 ELISA Kit

MBS9323148

48-Strip-Wells

470 USD

ELISA Kit

Human Ran-binding protein 9, RANBP9 ELISA Kit

[RAN binding protein 9]

[Human Ran-binding protein 9 (RANBP9) ELISA kit; RANBPM; novel centrosomal protein RanBPM; ran binding protein; centrosomal; RAN binding protein 9]

[ran-binding protein 9; Ran-binding protein 9; ran-binding protein 9; ran-binding protein M; novel centrosomal protein RanBPM; ran binding protein, centrosomal; Ran Binding Protein in the Microtubule organizing center; RAN binding protein 9; BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7]

[RANBP9]

[RANBP9; RANBP9; BPM-L; BPM90; RANBPM; RanBP7; RANBPM; RanBP9; RanBPM]

RANB9_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RANBP9 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

39812378

NP_005484.2

NM_005493.2

Q96S59

77,847 Da

Androgen Receptor Signaling Pathway (198806); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); L1CAM Interactions Pathway (161003); Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway (137930)

This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]

RANBP9: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Belongs to the RANBP9/10 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nuclear receptor co-regulator; GAPs; GAPs, Ras; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 6p23. Cellular Component: microtubule associated complex; nucleus; cytosol. Molecular Function: protein binding; enzyme binding; Ran GTPase binding. Biological Process: axon guidance; protein complex assembly; microtubule nucleation

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095