catalog number :
MBS9323041
products type :
ELISA Kit
products full name :
Mouse Histidyl-tRNA synthetase, cytoplasmic, HARS ELISA Kit
products short name :
[histidyl-tRNA synthetase]
products name syn :
[Mouse Histidyl-tRNA synthetase; cytoplasmic (HARS) ELISA kit; FLJ20491; HRS; HisRS; histidine tRNA ligase 1; cytoplasmic; histidine translase; histidine-tRNA ligase; histidyl-tRNA synthetase]
other names :
[histidine--tRNA ligase, cytoplasmic; Histidine--tRNA ligase, cytoplasmic; histidine--tRNA ligase, cytoplasmic; hisRS; histidine tRNA ligase; histidyl-tRNA synthetase, cytoplasmic; histidyl-tRNA synthetase; Histidyl-tRNA synthetase; HisRS]
products gene name :
[HARS]
other gene names :
[Hars; Hars; MMHRS; HisRS]
uniprot entry name :
SYHC_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HARS (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_032240.3
ncbi gb acc num :
NM_008214.4
ncbi mol weight :
57,432 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway (83227); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (421836); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (574712); Gene Expression Pathway (574654); TRNA Aminoacylation Pathway (574711)
uniprot summary :
HARS: Defects in HARS are a cause of Usher syndrome type 3B (USH3B). USH3B is a syndrome characterized by progressive vision and hearing loss during early childhood. Some patients have the so-called Charles Bonnet syndrome, involving decreased visual acuity and vivid visual hallucinations. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH3 is characterized by postlingual, progressive hearing loss, variable vestibular dysfunction, and onset of retinitis pigmentosa symptoms, including nyctalopia, constriction of the visual fields, and loss of central visual acuity, usually by the second decade of life. Belongs to the class-II aminoacyl-tRNA synthetase family. Protein type: Translation; Ligase; EC 6.1.1.21. Cellular Component: cytoplasm. Molecular Function: histidine-tRNA ligase activity; aminoacyl-tRNA ligase activity; nucleotide binding; ATP binding; ligase activity. Biological Process: tRNA aminoacylation for protein translation; translation; histidyl-tRNA aminoacylation
size4 :
10x96-Strip-Wells