catalog number :
MBS9322938
products type :
ELISA Kit
products full name :
Human Syntenin-1, SDCBP ELISA Kit
products short name :
[syndecan binding protein (syntenin)]
products name syn :
[Human Syntenin-1 (SDCBP) ELISA kit; MDA-9; ST1; SYCL; TACIP18; melanoma differentiation associated protein-9; pro-TGF-alpha cytoplasmic domain-interacting protein 18; scaffold protein Pbp1; syntenin; syndecan binding protein (syntenin)]
other names :
[syntenin-1 isoform 1; Syntenin-1; syntenin-1; scaffold protein Pbp1; syndecan-binding protein 1; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; pro-TGF-alpha cytoplasmic domain-interacting protein 18; syndecan binding protein (syntenin); Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1]
products gene name :
[SDCBP]
other gene names :
[SDCBP; SDCBP; ST1; SYCL; MDA-9; TACIP18; MDA9; SYCL; MDA-9; TACIP18]
uniprot entry name :
SDCB1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SDCBP1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001007068.1
ncbi gb acc num :
NM_001007067.1
ncbi mol weight :
32,444 Da
ncbi pathways :
Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); IL-5 Signaling Pathway (198770); L1CAM Interactions Pathway (161003); Neurofascin Interactions Pathway (161008); Syndecan-1-mediated Signaling Events Pathway (138046); Syndecan-2-mediated Signaling Events Pathway (138031); Syndecan-4-mediated Signaling Events Pathway (138064)
ncbi summary :
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
syntenin: Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Membrane protein, integral; Adaptor/scaffold; Motility/polarity/chemotaxis; Vesicle; Cell adhesion. Chromosomal Location of Human Ortholog: 8q12. Cellular Component: extracellular space; endoplasmic reticulum membrane; focal adhesion; cytosol; adherens junction; cytoskeleton; membrane; cytoplasm; melanosome; plasma membrane; interleukin-5 receptor complex; nucleus; vesicle. Molecular Function: syndecan binding; protein C-terminus binding; identical protein binding; protein homodimerization activity; ephrin receptor binding; protein N-terminus binding; interleukin-5 receptor binding; protein binding; protein heterodimerization activity; frizzled binding; growth factor binding; neurexin binding; cytoskeletal adaptor activity; cell adhesion molecule binding; glycoprotein binding. Biological Process: axon guidance; synaptic transmission; Ras protein signal transduction; ephrin receptor signaling pathway; positive regulation of JNK cascade; actin cytoskeleton organization and biogenesis; protein targeting to membrane; substrate-bound cell migration, cell extension; positive regulation of phosphorylation
size4 :
10x96-Strip-Wells