catalog number :
MBS9322721
products type :
ELISA Kit
products full name :
Human Pescadillo homolog, PES1 ELISA Kit
products short name :
[pescadillo homolog 1, containing BRCT domain (zebrafish)]
products name syn :
[Human Pescadillo homolog (PES1) ELISA kit; PES; pescadillo homolog 1; containing BRCT domain; pescadillo homolog 1; containing BRCT domain (zebrafish)]
other names :
[pescadillo homolog isoform 2; Pescadillo homolog; pescadillo homolog; pescadillo homolog 1, containing BRCT domain; pescadillo ribosomal biogenesis factor 1]
products gene name :
[PES1]
other gene names :
[PES1; PES1; PES]
uniprot entry name :
PESC_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PES1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001230154.1
ncbi gb acc num :
NM_001243225.1
ncbi mol weight :
68,003 Da
ncbi summary :
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]
uniprot summary :
PES1: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. Belongs to the pescadillo family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nucleolus; Translation; RNA-binding. Chromosomal Location of Human Ortholog: 22q12.1. Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; condensed chromosome; nucleus. Molecular Function: ribonucleoprotein binding; protein binding. Biological Process: cell proliferation; regulation of cell cycle; protein localization in organelle; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal large subunit biogenesis and assembly; rRNA processing; nucleolus organization and biogenesis
size4 :
10x96-Strip-Wells