catalog number :
MBS9322588
products type :
ELISA Kit
products full name :
Mouse Inhibitor of nuclear factor kappa-B kinase subunit epsilon, IKBKE ELISA Kit
products short name :
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
products name syn :
Mouse Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE) ELISA kit; RP11-534L20.1; IKK-i; IKKE; IKKI; KIAA0151; MGC125294; MGC125295; MGC125297; IKK-related kinase epsilon; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells; kinase epsilon
other names :
inhibitor of nuclear factor kappa-B kinase subunit epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKK-E; IKK-epsilon; I-kappa-B kinase epsilon; inducible IKappaB kinase; inducible I kappa-B kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; Inducible I kappa-B kinase; IKK-i
products gene name :
IKBKE
other gene names :
Ikbke; Ikbke; Ikki; IKK-i; AW558201; IKKepsilon; Ikke; Ikki; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; IKK-i
uniprot entry name :
IKKE_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 1.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IKBKE (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_062751.2
ncbi gb acc num :
NP_062751.2
ncbi mol weight :
80,953 Da
ncbi pathways :
Cytosolic DNA-sensing Pathway (125146); Cytosolic DNA-sensing Pathway (124833); Hepatitis C Pathway (173974); Hepatitis C Pathway (173907); Herpes Simplex Infection Pathway (377874); Herpes Simplex Infection Pathway (377865); Immune System Pathway (575095); Influenza A Pathway (217174); Influenza A Pathway (217150); Innate Immune System Pathway (575115)
uniprot summary :
IKKE: a oncogenic kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Plays a pivotal role in coordinating the activation of IRF3 and NF-kappaB in the innate immune response. Its redistribution to PML nuclear bodies upon DNA damage is TOPORS-dependent. Is a breast cancer oncogene that exerts its oncogenic properties through cRel. Protein type: Kinase, protein; EC 2.7.11.10; Inhibitor; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Other group; IKK family. Cellular Component: nucleoplasm; PML body; mitochondrial membrane; cytoplasm; nucleus. Molecular Function: NF-kappaB-inducing kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; IkappaB kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity. Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; I-kappaB phosphorylation; response to DNA damage stimulus; phosphorylation; protein amino acid phosphorylation