catalog number :
MBS9322403
products type :
ELISA Kit
products full name :
Mouse Myosin-3, MYH3 ELISA Kit
products short name :
[myosin, heavy chain 3, skeletal muscle, embryonic]
products name syn :
[Mouse Myosin-3 (MYH3) ELISA kit; HEMHC; MYHC-EMB; MYHSE1; SMHCE; myosin; heavy polypeptide 3; skeletal muscle; embryonic; myosin; skeletal; heavy chain; embryonic 1; myosin; heavy chain 3; skeletal muscle; embryonic]
other names :
[myosin-3; Myosin-3; myosin-3; myosin heavy chain 3; embryonic skeletal myosin heavy chain isoform; myosin, heavy polypeptide 3, skeletal muscle, embryonic; Myosin heavy chain 3]
products gene name :
[MYH3]
other gene names :
[Myh3; Myh3; Myhse; Myhs-e; MyHC-emb; Myhse]
uniprot entry name :
MYH3_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of MYH3 (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001093105.1
ncbi gb acc num :
NM_001099635.1
ncbi mol weight :
223,791 Da
ncbi pathways :
Muscle Contraction Pathway (971218); Striated Muscle Contraction Pathway (1000590); Striated Muscle Contraction Pathway (198348); Tight Junction Pathway (83268); Tight Junction Pathway (482)
ncbi summary :
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. [provided by RefSeq, Sep 2015]
uniprot summary :
MYH3: Muscle contraction. Defects in MYH3 are the cause of distal arthrogryposis type 2A (DA2A); also known as Freeman-Sheldon syndrome (FSS). Distal arthrogryposis is a clinically and genetically heterogeneous group of disorders characterized by bone anomalies and joint contractures of the hands and feet, causing medially overlapping fingers, clenched fists, ulnar deviation of fingers, camptodactyly and positional foot deformities. It is a disorder of primary limb malformation without primary neurologic or muscle disease. DA2A is the most severe form of distal arthrogryposis. Affected individuals have contractures of the orofacial muscles, characterized by microstomia with pouting lips, H-shaped dimpling of the chin, deep nasolabial folds, and blepharophimosis. Dysphagia, failure to thrive, growth deficit, and life-threatening respiratory complications (caused by structural anomalies of the oropharynx and upper airways) are frequent. Inheritance is autosomal dominant. Defects in MYH3 are the cause of distal arthrogryposis type 2B (DA2B); also known as Sheldon-Hall syndrome (SHS) or arthrogryposis multiplex congenita distal type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin. DA2B is the most common of the distal arthrogryposis syndromes. It is similar to DA2A but the facial contractures are less dramatic. Protein type: Motor; Motility/polarity/chemotaxis. Cellular Component: contractile fiber; cytoplasm; myosin complex. Molecular Function: calmodulin binding; actin filament binding; microfilament motor activity; motor activity; nucleotide binding; actin binding; ATP binding. Biological Process: skeletal muscle contraction; metabolic process
size4 :
10x96-Strip-Wells