product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human guanylate cyclase activator 2B (uroguanylin) , GUCA2B ELISA Kit
catalog :
MBS932232
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS932232
products type :
ELISA Kit
products full name :
Human guanylate cyclase activator 2B (uroguanylin) , GUCA2B ELISA Kit
products short name :
guanylate cyclase activator 2B (uroguanylin)
products name syn :
Human guanylate cyclase activator 2B (uroguanylin) (GUCA2B) ELISA kit; GCAP-II; UGN; guanylate cyclase activator 2B; uroguanylin; guanylate cyclase activator 2B (uroguanylin)
other names :
guanylate cyclase activator 2B; Guanylate cyclase activator 2B; guanylate cyclase activator 2B; uroguanylin; prepro-uroguanylin; guanylate cyclase activator 2B (uroguanylin); Guanylate cyclase C-activating peptide II; GCAP-II
products gene name :
GUCA2B
other gene names :
GUCA2B; GUCA2B; UGN; GCAP-II; GCAP-II; UGN
uniprot entry name :
GUC2B_HUMAN
reactivity :
Human
sequence length :
112
specificity :
This assay has high sensitivity and excellent specificity for detection of human GUCA2B. No significant cross-reactivity or interference between human GUCA2B and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, urine and cell culture supernates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml -2000 pg/ml. Sensitivity: 7.8 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GUCA2B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GUCA2B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GUCA2B is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GUCA2B bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
6005774
ncbi acc num :
NP_009033.1
ncbi gb acc num :
NM_007102.2
uniprot acc num :
Q16661
ncbi mol weight :
12,069 Da
ncbi pathways :
Myometrial Relaxation And Contraction Pathways (198759)
ncbi summary :
This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
uniprot summary :
GUCA2B: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. Belongs to the guanylin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1p34-p33. Molecular Function: calcium sensitive guanylate cyclase activator activity. Biological Process: cGMP biosynthetic process; positive regulation of guanylate cyclase activity; negative regulation of blood pressure; excretion; body fluid secretion
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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