Mouse C-X-C motif chemokine 3, CXCL3 ELISA Kit | MyBioSource MBS932211 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse C-X-C motif chemokine 3, CXCL3 ELISA Kit

catalog :

MBS932211

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS932211

products type :

ELISA Kit

products full name :

Mouse C-X-C motif chemokine 3, CXCL3 ELISA Kit

products short name :

chemokine (C-X-C motif) ligand 3

products name syn :

Mouse C-X-C motif chemokine 3 (CXCL3) ELISA kit; CINC-2b; GRO3; GROg; MIP-2b; MIP2B; SCYB3; GRO3 oncogene; MGSA gamma; melanoma growth stimulatory activity gamma; chemokine (C-X-C motif) ligand 3

other names :

C-X-C motif chemokine 3; C-X-C motif chemokine 3; C-X-C motif chemokine 3; dendritic cell inflammatory protein 1; chemokine (C-X-C motif) ligand 3; Dendritic cell inflammatory protein 1

products gene name :

CXCL3

other gene names :

Cxcl3; Cxcl3; Dcip1; Gm1960; Dcip1; Gm1960

uniprot entry name :

CXCL3_MOUSE

reactivity :

Mouse

sequence length :

100

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse CXCL3. No significant cross-reactivity or interference between mouse CXCL3 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 7.8 pg/ml -500 pg/ml. Sensitivity: The minimum detectable dose of mouse CXCL3 is typically less than 1.95 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CXCL3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CXCL3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXCL3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXCL3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

42600573

ncbi acc num :

NP_976065.1

ncbi gb acc num :

NM_203320.3

uniprot acc num :

Q6W5C0

ncbi mol weight :

10,686 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (1000944); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1000942); Cytokines And Inflammatory Response (BioCarta) Pathway (198283); G Alpha (i) Signalling Events Pathway (1000973); GPCR Downstream Signaling Pathway (1000971); GPCR Ligand Binding Pathway (1000941); Legionellosis Pathway (469202); Legionellosis Pathway (469186)

ncbi summary :

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. [provided by RefSeq, May 2013]

uniprot summary :

CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted. Cellular Component: extracellular space; cell; extracellular region; cytosol. Molecular Function: protein binding; chemokine activity; CXCR chemokine receptor binding; cytokine activity. Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of leukocyte chemotaxis; immune response; response to lipopolysaccharide; chemotaxis; inflammatory response; regulation of cell proliferation

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage