catalog number :
MBS9321965
products type :
ELISA Kit
products full name :
Human DnaJ homolog subfamily B member 11, DNAJB11 ELISA Kit
products short name :
[DnaJ (Hsp40) homolog, subfamily B, member 11]
products name syn :
[Human DnaJ homolog subfamily B member 11 (DNAJB11) ELISA kit; ABBP-2; ABBP2; DJ9; EDJ; ERdj3; ERj3; HEDJ; PRO1080; UNQ537; hDj9; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; OTTHUMP00000210171; PWP1-interacting protein 4; DnaJ (Hsp40) homolog; subfamily B; member 11]
other names :
[dnaJ homolog subfamily B member 11; DnaJ homolog subfamily B member 11; dnaJ homolog subfamily B member 11; DnaJ protein 9; APOBEC1-binding protein 2; ER-resident protein ERdj3; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; endoplasmic reticulum DNA J domain-containing protein 3; DnaJ (Hsp40) homolog, subfamily B, member 11; APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4]
products gene name :
[DNAJB11]
other gene names :
[DNAJB11; DNAJB11; DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080; EDJ; ERJ3; HDJ9; PSEC0121; UNQ537/PRO1080; ABBP-2; ER-resident protein ERdj3; ERdj3; ERj3p; hDj-9]
uniprot entry name :
DJB11_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DNAJB11 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_057390.1
ncbi gb acc num :
NM_016306.5
ncbi mol weight :
40,514 Da
ncbi pathways :
IRE1alpha Activates Chaperones Pathway (105906); Metabolism Of Proteins Pathway (106230); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190); Unfolded Protein Response (UPR) Pathway (105904); XBP1(S) Activates Chaperone Genes Pathway (530771)
ncbi summary :
This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014]
uniprot summary :
Function: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.2 PublicationsManual assertion based on experiment in:Ref.2
size4 :
10x96-Strip-Wells